Combating biofilms

Liang Yang, Yang Liu, Hong Wu, Zhijun Song, Niels Hoiby, Søren Molin, Michael Givskov

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Abstract

Biofilms are complex microbial communities consisting of microcolonies embedded in a matrix of self-produced polymer substances. Biofilm cells show much greater resistance to environmental challenges including antimicrobial agents than their free-living counterparts. The biofilm mode of life is believed to significantly contribute to successful microbial survival in hostile environments. Conventional treatment, disinfection and cleaning strategies do not proficiently deal with biofilm-related problems, such as persistent infections and contamination of food production facilities. In this review, strategies to control biofilms are discussed, including those of inhibition of microbial attachment, interference of biofilm structure development and differentiation, killing of biofilm cells and induction of biofilm dispersion.
Original languageEnglish
JournalF E M S Immunology and Medical Microbiology
Volume65
Issue number2, Sp. Iss. SI
Pages (from-to)146-157
ISSN0928-8244
DOIs
Publication statusPublished - 2012

Fingerprint Dive into the research topics of 'Combating biofilms'. Together they form a unique fingerprint.

Cite this