Transport in the edge and scrape-off layer mediated by turbulent fluctuations is often studied using drift fluid models. In this work, we expand previous work on a two-fluid single ion species drift model to a multi-ion-species model that incorporates collisional interactions between the individual species while conserving energy. The model is simplified into a set of equations that are computationally realizable. This is used to study the dependency of seeded blob propagation on different mixes of deuterium and tritium isotopes in the background and blob, respectively. We find that the background mix is initially the dominant driver that determines propagation, but the blob mix becomes the dominating factor for continued evolution. It is found that the maximum velocity of the blob scales stronger with the initial blob mix than the background mix.