Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy

M. Walther; P. Plochocka; B. Fischer; H. Helm; Peter Uhd Jepsen

doi:10.1002/bip.10106

Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy

M. Walther, P. Plochocka, B. Fischer, H. Helm, Peter Uhd Jepsen

Research output: Contribution to journal › Conference article › Research › peer-review

Abstract

We present well-resolved absorption spectra of biological molecules in the far-IR (FIR) spectral region recorded by terahertz time-domain spectroscopy (THzTDS). As an illustrative example we discuss the absorption spectra of benzoic acid, its monosubstitutes salicylic acid (2-hydroxy-benzoic acid), 3- and 4-hydroxybenzoic acid, and aspirin (acetylsalicylic acid) in the spectral region between 18 and 150 cm(-1). The spectra exhibit distinct features originating from low-frequency vibrational modes caused by intra- or intermolecular collective motion and lattice modes. Due to the collective origin of the observed modes the absorption spectra are highly sensitive to the overall structure and configuration of the molecules, as well as their environment. The THz-TDS procedure can provide a direct fingerprint of the molecular structure or conformational state of a compound. (C) 2002 Wiley Periodicals, Inc.

Original language	English
Journal	Biopolymers
Volume	67
Issue number	4-5
Pages (from-to)	310-313
Number of pages	4
ISSN	0006-3525
DOIs	https://doi.org/10.1002/bip.10106
Publication status	Published - 2002
Externally published	Yes
Event	9th European Conference on the Spectroscopy of Biological Molecules - Prague, Czech Republic Duration: 8 Sept 2001 → 13 Sept 2001 Conference number: 9 https://www.ecsbm.eu/node/2

Conference

Conference	9th European Conference on the Spectroscopy of Biological Molecules
Number	9
Country/Territory	Czech Republic
City	Prague
Period	08/09/2001 → 13/09/2001
Internet address	https://www.ecsbm.eu/node/2

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title = "Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy",

abstract = "We present well-resolved absorption spectra of biological molecules in the far-IR (FIR) spectral region recorded by terahertz time-domain spectroscopy (THzTDS). As an illustrative example we discuss the absorption spectra of benzoic acid, its monosubstitutes salicylic acid (2-hydroxy-benzoic acid), 3- and 4-hydroxybenzoic acid, and aspirin (acetylsalicylic acid) in the spectral region between 18 and 150 cm(-1). The spectra exhibit distinct features originating from low-frequency vibrational modes caused by intra- or intermolecular collective motion and lattice modes. Due to the collective origin of the observed modes the absorption spectra are highly sensitive to the overall structure and configuration of the molecules, as well as their environment. The THz-TDS procedure can provide a direct fingerprint of the molecular structure or conformational state of a compound. (C) 2002 Wiley Periodicals, Inc. ",

author = "M. Walther and P. Plochocka and B. Fischer and H. Helm and Jepsen, {Peter Uhd}",

year = "2002",

doi = "10.1002/bip.10106",

language = "English",

volume = "67",

pages = "310--313",

journal = "Biopolymers",

issn = "0006-3525",

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TY - GEN

T1 - Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy

AU - Walther, M.

AU - Plochocka, P.

AU - Fischer, B.

AU - Helm, H.

AU - Jepsen, Peter Uhd

N1 - Conference code: 9

PY - 2002

Y1 - 2002

N2 - We present well-resolved absorption spectra of biological molecules in the far-IR (FIR) spectral region recorded by terahertz time-domain spectroscopy (THzTDS). As an illustrative example we discuss the absorption spectra of benzoic acid, its monosubstitutes salicylic acid (2-hydroxy-benzoic acid), 3- and 4-hydroxybenzoic acid, and aspirin (acetylsalicylic acid) in the spectral region between 18 and 150 cm(-1). The spectra exhibit distinct features originating from low-frequency vibrational modes caused by intra- or intermolecular collective motion and lattice modes. Due to the collective origin of the observed modes the absorption spectra are highly sensitive to the overall structure and configuration of the molecules, as well as their environment. The THz-TDS procedure can provide a direct fingerprint of the molecular structure or conformational state of a compound. (C) 2002 Wiley Periodicals, Inc.

AB - We present well-resolved absorption spectra of biological molecules in the far-IR (FIR) spectral region recorded by terahertz time-domain spectroscopy (THzTDS). As an illustrative example we discuss the absorption spectra of benzoic acid, its monosubstitutes salicylic acid (2-hydroxy-benzoic acid), 3- and 4-hydroxybenzoic acid, and aspirin (acetylsalicylic acid) in the spectral region between 18 and 150 cm(-1). The spectra exhibit distinct features originating from low-frequency vibrational modes caused by intra- or intermolecular collective motion and lattice modes. Due to the collective origin of the observed modes the absorption spectra are highly sensitive to the overall structure and configuration of the molecules, as well as their environment. The THz-TDS procedure can provide a direct fingerprint of the molecular structure or conformational state of a compound. (C) 2002 Wiley Periodicals, Inc.

U2 - 10.1002/bip.10106

DO - 10.1002/bip.10106

M3 - Conference article

SN - 0006-3525

VL - 67

SP - 310

EP - 313

JO - Biopolymers

JF - Biopolymers

IS - 4-5

T2 - 9th European Conference on the Spectroscopy of Biological Molecules

Y2 - 8 September 2001 through 13 September 2001

ER -

Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy

Abstract

Conference

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