Collective Phenomena in Kidney Autoregulation

Erik Mosekilde, Olga Sosnovtseva, N.-H. Holstein-Rathlou

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

By controling the excretion of water and salts, the kidneys play all important role ill regulating the blood pressure and maintaining a proper environment for the cells of the body. This control depends to a large extent oil mechanisms that are associated with the individual functional unit, the nephron. However, a variety of cooperative phenomena arising through interactions between the nephrons may also be important. We prescut experimental evidence for a coupling between nephrons that are connected via a common piece of afferent arteriole. We also develop a mathematical model that call account for the observed synchronization phenomena, and discuss the possible physiological significance of these phenomena. We are particularly interested ill synchronization effects that call occur among neighboring nephrons that individually display irregular (or chaotic) dynamics in their pressure and flow regulation.
Original languageEnglish
Title of host publicationSimplicity Behind Complexity
EditorsW. Klonowski
Place of PublicationGermany
PublisherPabst Science Publishers
Publication date2004
Pages110-145
ISBN (Print)3-89967-070-1
Publication statusPublished - 2004
EventEuropean Interdisciplinary School on Nonlinear Dynamics for System and Signal Analysis - Warsaw, Poland
Duration: 18 Jun 200227 Jun 2002
Conference number: 3

Conference

ConferenceEuropean Interdisciplinary School on Nonlinear Dynamics for System and Signal Analysis
Number3
CountryPoland
CityWarsaw
Period18/06/200227/06/2002
SeriesFRONTIERS ON NONLINEAR DYNAMICS
Volume3

Keywords

  • collective phenomena
  • nephron
  • coupled oscillators
  • chaotic synchronization

Cite this

Mosekilde, E., Sosnovtseva, O., & Holstein-Rathlou, N-H. (2004). Collective Phenomena in Kidney Autoregulation. In W. Klonowski (Ed.), Simplicity Behind Complexity (pp. 110-145). Germany: Pabst Science Publishers. FRONTIERS ON NONLINEAR DYNAMICS, Vol.. 3