Coil profile estimation strategies for parallel imaging with hyperpolarized 13C MRI

Rie Beck Hansen, Juan Diego Sánchez-Heredia, Nikolaj Bøgh, Esben Søvsø Szocska Hansen, Christoffer Laustsen, Lars G. Hanson, Jan Henrik Ardenkjær-Larsen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Purpose: To investigate auto- and pre-calibration coil profile estimation for parallel imaging reconstruction of hyperpolarized 13C MRI volumetric data. Methods: Parallel imaging reconstruction was studied with 3 different approaches for coil profile estimation: auto-calibration, phantom calibration, and theoretic calibration. Acquisition was performed with a 3D stack-of-spirals sequence with spectral–spatial excitation and Cartesian undersampling. Parallel imaging reconstructions were done with conjugate gradient SENSE and 3D gridding with inhomogeneity correction. The approaches were compared in simulations with different SNR, through phantom experiments, and in an in vivo pig study focused on the kidneys. All imaging was done with a rigid home-built 12-channel 13C receive coil at 3T. Results: The phantom calibrated and theoretic approaches resulted in the best structural similarities in simulations and demonstrated higher image quality in the phantom experiments compared to the auto-calibrated approach. In vivo mapping of pyruvate uptake and lactate conversion improved for accelerated acquisitions because of a better temporal resolution. From a practical and image quality point of view, use of theoretic coil profiles led to improved results compared to the other approaches. Conclusion: The success of the theoretic coil profile estimation demonstrates a negligible effect of load on sensitivity profiles at the carbon frequency at 3T. Through theoretic or phantom calibrated parallel imaging, accelerated 3D volumes could be reconstructed with sufficient sensitivity, temporal, and spatial resolution to map the metabolism of kidneys exemplifying abdominal organs. This approach overcomes a critical step in the clinical translation of parallel imaging in hyperpolarized 13C MR.
Original languageEnglish
JournalMagnetic Resonance in Medicine
Volume82
Issue number6
Pages (from-to)2104-2117
ISSN0740-3194
DOIs
Publication statusPublished - 2019

Keywords

  • Coil sensitivity estimation
  • Hyperpolarization
  • Metabolic imaging
  • Parallel imaging
  • RF coil array
  • 13C MRI

Cite this

@article{df0d1c77bd2b48bdbf9cbe4eee6d4fae,
title = "Coil profile estimation strategies for parallel imaging with hyperpolarized 13C MRI",
abstract = "Purpose: To investigate auto- and pre-calibration coil profile estimation for parallel imaging reconstruction of hyperpolarized 13C MRI volumetric data. Methods: Parallel imaging reconstruction was studied with 3 different approaches for coil profile estimation: auto-calibration, phantom calibration, and theoretic calibration. Acquisition was performed with a 3D stack-of-spirals sequence with spectral–spatial excitation and Cartesian undersampling. Parallel imaging reconstructions were done with conjugate gradient SENSE and 3D gridding with inhomogeneity correction. The approaches were compared in simulations with different SNR, through phantom experiments, and in an in vivo pig study focused on the kidneys. All imaging was done with a rigid home-built 12-channel 13C receive coil at 3T. Results: The phantom calibrated and theoretic approaches resulted in the best structural similarities in simulations and demonstrated higher image quality in the phantom experiments compared to the auto-calibrated approach. In vivo mapping of pyruvate uptake and lactate conversion improved for accelerated acquisitions because of a better temporal resolution. From a practical and image quality point of view, use of theoretic coil profiles led to improved results compared to the other approaches. Conclusion: The success of the theoretic coil profile estimation demonstrates a negligible effect of load on sensitivity profiles at the carbon frequency at 3T. Through theoretic or phantom calibrated parallel imaging, accelerated 3D volumes could be reconstructed with sufficient sensitivity, temporal, and spatial resolution to map the metabolism of kidneys exemplifying abdominal organs. This approach overcomes a critical step in the clinical translation of parallel imaging in hyperpolarized 13C MR.",
keywords = "Coil sensitivity estimation, Hyperpolarization, Metabolic imaging, Parallel imaging, RF coil array, 13C MRI",
author = "Hansen, {Rie Beck} and S{\'a}nchez-Heredia, {Juan Diego} and Nikolaj B{\o}gh and Hansen, {Esben S{\o}vs{\o} Szocska} and Christoffer Laustsen and Hanson, {Lars G.} and Ardenkj{\ae}r-Larsen, {Jan Henrik}",
year = "2019",
doi = "10.1002/mrm.27892",
language = "English",
volume = "82",
pages = "2104--2117",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "JohnWiley & Sons, Inc.",
number = "6",

}

Coil profile estimation strategies for parallel imaging with hyperpolarized 13C MRI. / Hansen, Rie Beck; Sánchez-Heredia, Juan Diego; Bøgh, Nikolaj; Hansen, Esben Søvsø Szocska; Laustsen, Christoffer; Hanson, Lars G. ; Ardenkjær-Larsen, Jan Henrik.

In: Magnetic Resonance in Medicine, Vol. 82, No. 6, 2019, p. 2104-2117.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Coil profile estimation strategies for parallel imaging with hyperpolarized 13C MRI

AU - Hansen, Rie Beck

AU - Sánchez-Heredia, Juan Diego

AU - Bøgh, Nikolaj

AU - Hansen, Esben Søvsø Szocska

AU - Laustsen, Christoffer

AU - Hanson, Lars G.

AU - Ardenkjær-Larsen, Jan Henrik

PY - 2019

Y1 - 2019

N2 - Purpose: To investigate auto- and pre-calibration coil profile estimation for parallel imaging reconstruction of hyperpolarized 13C MRI volumetric data. Methods: Parallel imaging reconstruction was studied with 3 different approaches for coil profile estimation: auto-calibration, phantom calibration, and theoretic calibration. Acquisition was performed with a 3D stack-of-spirals sequence with spectral–spatial excitation and Cartesian undersampling. Parallel imaging reconstructions were done with conjugate gradient SENSE and 3D gridding with inhomogeneity correction. The approaches were compared in simulations with different SNR, through phantom experiments, and in an in vivo pig study focused on the kidneys. All imaging was done with a rigid home-built 12-channel 13C receive coil at 3T. Results: The phantom calibrated and theoretic approaches resulted in the best structural similarities in simulations and demonstrated higher image quality in the phantom experiments compared to the auto-calibrated approach. In vivo mapping of pyruvate uptake and lactate conversion improved for accelerated acquisitions because of a better temporal resolution. From a practical and image quality point of view, use of theoretic coil profiles led to improved results compared to the other approaches. Conclusion: The success of the theoretic coil profile estimation demonstrates a negligible effect of load on sensitivity profiles at the carbon frequency at 3T. Through theoretic or phantom calibrated parallel imaging, accelerated 3D volumes could be reconstructed with sufficient sensitivity, temporal, and spatial resolution to map the metabolism of kidneys exemplifying abdominal organs. This approach overcomes a critical step in the clinical translation of parallel imaging in hyperpolarized 13C MR.

AB - Purpose: To investigate auto- and pre-calibration coil profile estimation for parallel imaging reconstruction of hyperpolarized 13C MRI volumetric data. Methods: Parallel imaging reconstruction was studied with 3 different approaches for coil profile estimation: auto-calibration, phantom calibration, and theoretic calibration. Acquisition was performed with a 3D stack-of-spirals sequence with spectral–spatial excitation and Cartesian undersampling. Parallel imaging reconstructions were done with conjugate gradient SENSE and 3D gridding with inhomogeneity correction. The approaches were compared in simulations with different SNR, through phantom experiments, and in an in vivo pig study focused on the kidneys. All imaging was done with a rigid home-built 12-channel 13C receive coil at 3T. Results: The phantom calibrated and theoretic approaches resulted in the best structural similarities in simulations and demonstrated higher image quality in the phantom experiments compared to the auto-calibrated approach. In vivo mapping of pyruvate uptake and lactate conversion improved for accelerated acquisitions because of a better temporal resolution. From a practical and image quality point of view, use of theoretic coil profiles led to improved results compared to the other approaches. Conclusion: The success of the theoretic coil profile estimation demonstrates a negligible effect of load on sensitivity profiles at the carbon frequency at 3T. Through theoretic or phantom calibrated parallel imaging, accelerated 3D volumes could be reconstructed with sufficient sensitivity, temporal, and spatial resolution to map the metabolism of kidneys exemplifying abdominal organs. This approach overcomes a critical step in the clinical translation of parallel imaging in hyperpolarized 13C MR.

KW - Coil sensitivity estimation

KW - Hyperpolarization

KW - Metabolic imaging

KW - Parallel imaging

KW - RF coil array

KW - 13C MRI

U2 - 10.1002/mrm.27892

DO - 10.1002/mrm.27892

M3 - Journal article

VL - 82

SP - 2104

EP - 2117

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 6

ER -