Abstract
A theory is presented for coherent topological phenomena in
protein dynamics with implications for protein folding and
stability. We discuss the relationship to the writhing number used
in knot diagrams of DNA. The winding state defines a long-range
order along the backbone of a protein with long-range excitations,
`wring' modes, that play an important role in protein denaturation
and stability. Energy can be pumped into these excitations, either
thermally or by an external force.
| Original language | English |
|---|---|
| Journal | Folding and Design |
| Volume | 2 |
| Pages (from-to) | S15-S18 |
| ISSN | 1359-0278 |
| Publication status | Published - 1997 |
| Event | Distance-Based Approaches to Protein Structure
Determination III - Copenhagen Duration: 1 Jan 1996 → … |
Conference
| Conference | Distance-Based Approaches to Protein Structure Determination III |
|---|---|
| City | Copenhagen |
| Period | 01/01/1996 → … |