"Clickable" LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

Anna S. Jorgensen, Pankaj Gupta, Jesper Wengel, Kira Astakhova

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Abstract

Herein we describe fluorescent oligonucleotides prepared by click chemistry between novel alkyne-modified locked nucleic acid (LNA) strands and a series of fluorescent azides for homogeneous (all-in-solution) detection of nucleic acids and autoimmune antibodies.
Original languageEnglish
JournalChemical Communications
Volume49
Issue number91
Pages (from-to)10751-10753
Number of pages3
ISSN1359-7345
DOIs
Publication statusPublished - 2013
Externally publishedYes

Bibliographical note

Open Access Article. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

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