Cleaving Double-Stranded DNA with Peptide Nucleic Acids

David J. Ecker; Ole Buchardt; Michael Engholm; Peter E. Nielsen; Rolf Henrik Berg; Niels E. Møllegaard

Cleaving Double-Stranded DNA with Peptide Nucleic Acids

David J. Ecker (Inventor)
, Ole Buchardt (Inventor)
, Michael Engholm (Inventor)
, Peter E. Nielsen (Inventor)
, Rolf Henrik Berg (Inventor)
, Niels E. Møllegaard (Inventor)

Ionis Pharmaceuticals
University of Copenhagen

Research output: Patent

127 Downloads (Orbit)

Abstract

Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.

Original language	English
Patent number	US5641625
Filing date	24/06/1997
Country/Territory	Denmark
Publication status	Published - 1997

Bibliographical note

Also published as: WO9501370 (A1) US5986053 (A) JPH09503198 (A) JPH11236396 (A) ES2187527 (T3) EP0776331 (A1) EP0776331 (A4) EP0776331 (B1) DK0776331 (T3) DE69431805 (T2) CA2166461 (A1) AT228534 (T)

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title = "Cleaving Double-Stranded DNA with Peptide Nucleic Acids",

abstract = "Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.",

author = "Ecker, \{David J.\} and Ole Buchardt and Michael Engholm and Nielsen, \{Peter E.\} and Berg, \{Rolf Henrik\} and M{\o}llegaard, \{Niels E.\}",

note = "Also published as: WO9501370 (A1) US5986053 (A) JPH09503198 (A) JPH11236396 (A) ES2187527 (T3) EP0776331 (A1) EP0776331 (A4) EP0776331 (B1) DK0776331 (T3) DE69431805 (T2) CA2166461 (A1) AT228534 (T) ; US5641625",

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AU - Ecker, David J.

AU - Buchardt, Ole

AU - Engholm, Michael

AU - Nielsen, Peter E.

AU - Berg, Rolf Henrik

AU - Møllegaard, Niels E.

N1 - Also published as: WO9501370 (A1) US5986053 (A) JPH09503198 (A) JPH11236396 (A) ES2187527 (T3) EP0776331 (A1) EP0776331 (A4) EP0776331 (B1) DK0776331 (T3) DE69431805 (T2) CA2166461 (A1) AT228534 (T)

PY - 1997

Y1 - 1997

N2 - Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.

AB - Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.

M3 - Patent

M1 - US5641625

Y2 - 1997/06/24

ER -

Cleaving Double-Stranded DNA with Peptide Nucleic Acids

Abstract

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