cIAP1/2 antagonization by SMAC mimetic induces non-canonical NF-κB mediated TH17 cell homotypic interactions and increases their resistance to shear stress

John Rizk, Rasmus Agerholm, Alexander Jönsson, Asli Aybike Dogan, Martin Dufva, Vasileios Bekiaris*

*Corresponding author for this work

Research output: Contribution to journalLetterpeer-review

Original languageEnglish
JournalEuropean Journal of Immunology
Issue number8
Pages (from-to)2097-2099
Publication statusPublished - 2021

Bibliographical note

Funding Information:
We thank Professor Ari Waisman (Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg, University of Mainz, Germany) for providing organs from CD4CRE- NIKF/F mice. This work and V.B. were supported by Lundbeck Foundation grant R163-2013-15201. J.R. and R.A. were supported by DTU PhD. scholarships. M.D. was supported by Innovation Fund Denmark (IFD) grant 8090-00009B and Organovir grant 812673.


  • cIAP1/2
  • NF-κB
  • Shear stress
  • SMAC
  • T17

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