TY - JOUR
T1 - Chronic kidney failure following lancehead bite envenoming: a clinical report from the Amazon region
AU - Pucca, Manuela B.
AU - Franco, Michelle V. S.
AU - Medeiros, Jilvando M.
AU - Oliveira, Isadora S.
AU - Ahmadi, Shirin
AU - Cerni, Felipe A.
AU - Zottich, Umberto
AU - Bassoli, Bruna K.
AU - Monteiro, Wuelton M.
AU - Laustsen, Andreas H.
PY - 2020
Y1 - 2020
N2 - Background: Snakebite envenoming can be a life-threatening condition, for which emergency care is essential. The Bothrops (lancehead) genus isresponsible for most snakebite-related deaths and permanent loss of function in human victims in Latin America. Bothrops spp. venom is a complex mixture of different proteins that are known to cause local necrosis, coagulopathy, and acute kidney injury. However, the long-term effects of these viper envenomings have remained largely understudied. Case presentation: Here, we present a case report of a 46-years old female patient from Las Claritas, Venezuela, who was envenomed by a snake from the Bothrops genus. The patient was followed for a 10-year period, during which she presented oliguric renal failure, culminating in kidney failure 60 months after the envenoming. Conclusion: In Latin America, especially in Brazil, where there is a high prevalence of Bothrops envenoming, it may be relevant to establish long-term outpatient programs. This would reduce late adverse events, such as chronic kidney disease, and optimize public financial resources by avoiding hemodialysis and consequently kidney transplantation.
AB - Background: Snakebite envenoming can be a life-threatening condition, for which emergency care is essential. The Bothrops (lancehead) genus isresponsible for most snakebite-related deaths and permanent loss of function in human victims in Latin America. Bothrops spp. venom is a complex mixture of different proteins that are known to cause local necrosis, coagulopathy, and acute kidney injury. However, the long-term effects of these viper envenomings have remained largely understudied. Case presentation: Here, we present a case report of a 46-years old female patient from Las Claritas, Venezuela, who was envenomed by a snake from the Bothrops genus. The patient was followed for a 10-year period, during which she presented oliguric renal failure, culminating in kidney failure 60 months after the envenoming. Conclusion: In Latin America, especially in Brazil, where there is a high prevalence of Bothrops envenoming, it may be relevant to establish long-term outpatient programs. This would reduce late adverse events, such as chronic kidney disease, and optimize public financial resources by avoiding hemodialysis and consequently kidney transplantation.
U2 - 10.1590/1678-9199-JVATITD-2020-0083
DO - 10.1590/1678-9199-JVATITD-2020-0083
M3 - Journal article
C2 - 33424950
VL - 26
JO - Journal of Venomous Animals and Toxins Including Tropical Diseases
JF - Journal of Venomous Animals and Toxins Including Tropical Diseases
SN - 1678-9199
M1 - e20200083
ER -