CHO On A Detox: Removing By-Product Formation Through Cell Engineering

Sara Pereira; Helene Faustrup Kildegaard; Mikael Rørdam Andersen

CHO On A Detox: Removing By-Product Formation Through Cell Engineering

Sara Pereira, Helene Faustrup Kildegaard, Mikael Rørdam Andersen

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Abstract

Chinese Hamster Ovary (CHO) cells are the preferred hosts for the production of therapeutic glycoproteins. However, there is a need for improvement of the bioprocesses towards increased cell growth and higher productivities without compromising the product quality. Efforts to obtain tailor-made products with the desired properties that meet the requirements of regulatory authorities are continuously being made. Of equal relevance is to develop methods to engineer cell lines with improved by-product metabolism.

Original language	English
Publication date	2016
Number of pages	1
Publication status	Published - 2016
Event	1st ESACT Frontiers Retreat - Lyon, France Duration: 20 Oct 2016 → 22 Oct 2016 Conference number: 1

Conference

Conference	1st ESACT Frontiers Retreat
Number	1
Country/Territory	France
City	Lyon
Period	20/10/2016 → 22/10/2016

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1st ESACT Frontiers Retreat
Pereira, S. (Participant)
20 Oct 2016 → 22 Oct 2016
Activity: Attending an event › Participating in or organising a conference

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title = "CHO On A Detox: Removing By-Product Formation Through Cell Engineering",

abstract = "Chinese Hamster Ovary (CHO) cells are the preferred hosts for the production of therapeutic glycoproteins. However, there is a need for improvement of the bioprocesses towards increased cell growth and higher productivities without compromising the product quality. Efforts to obtain tailor-made products with the desired properties that meet the requirements of regulatory authorities are continuously being made. Of equal relevance is to develop methods to engineer cell lines with improved by-product metabolism.",

author = "Sara Pereira and Kildegaard, {Helene Faustrup} and Andersen, {Mikael R{\o}rdam}",

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T1 - CHO On A Detox: Removing By-Product Formation Through Cell Engineering

AU - Pereira, Sara

AU - Kildegaard, Helene Faustrup

AU - Andersen, Mikael Rørdam

N1 - Conference code: 1

PY - 2016

Y1 - 2016

N2 - Chinese Hamster Ovary (CHO) cells are the preferred hosts for the production of therapeutic glycoproteins. However, there is a need for improvement of the bioprocesses towards increased cell growth and higher productivities without compromising the product quality. Efforts to obtain tailor-made products with the desired properties that meet the requirements of regulatory authorities are continuously being made. Of equal relevance is to develop methods to engineer cell lines with improved by-product metabolism.

AB - Chinese Hamster Ovary (CHO) cells are the preferred hosts for the production of therapeutic glycoproteins. However, there is a need for improvement of the bioprocesses towards increased cell growth and higher productivities without compromising the product quality. Efforts to obtain tailor-made products with the desired properties that meet the requirements of regulatory authorities are continuously being made. Of equal relevance is to develop methods to engineer cell lines with improved by-product metabolism.

M3 - Conference abstract for conference

T2 - 1st ESACT Frontiers Retreat

Y2 - 20 October 2016 through 22 October 2016

ER -

CHO On A Detox: Removing By-Product Formation Through Cell Engineering

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