Children developing asthma by school-age display aberrant immune responses to pathogenic airway bacteria as infants

Jeppe Madura Larsen; Susanne Brix Pedersen; Anna Hammerich Thysen; S. Birch; M.A. Rasmussen; H. Bisgaard

Children developing asthma by school-age display aberrant immune responses to pathogenic airway bacteria as infants

Jeppe Madura Larsen, Susanne Brix Pedersen, Anna Hammerich Thysen, S. Birch, M.A. Rasmussen, H. Bisgaard

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Abstract

Asthma is a highly prevalent chronic lung disease that commonly originates in early childhood. Colonisation of neonatal airways with the pathogenic bacterial strains H. influenzae, M. catarrhalis and S. pneumoniae is associated with increased risk of later childhood asthma. We hypothesized that children developing asthma have an abnormal immune response to pathogenic bacteria in infancy. We aimed to assess the bacterial immune response in asymptomatic infants and the
association with later development of asthma by age 7 years.

Original language	English
Article number	404
Journal	Allergy
Volume	69
Issue number	s99
Pages (from-to)	179-179
Number of pages	1
ISSN	0105-4538
Publication status	Published - 2014
Event	European Academy of Allergy and Clinical Immunology Congress 2014 - Copenhagen, Denmark Duration: 7 Jun 2014 → 11 Jun 2014 Conference number: 33 https://onlinelibrary.wiley.com/toc/13989995/2014/69/s99

Conference

Conference	European Academy of Allergy and Clinical Immunology Congress 2014
Number	33
Country/Territory	Denmark
City	Copenhagen
Period	07/06/2014 → 11/06/2014
Internet address	https://onlinelibrary.wiley.com/toc/13989995/2014/69/s99

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title = "Children developing asthma by school-age display aberrant immune responses to pathogenic airway bacteria as infants",

abstract = "Asthma is a highly prevalent chronic lung disease that commonly originates in early childhood. Colonisation of neonatal airways with the pathogenic bacterial strains H. influenzae, M. catarrhalis and S. pneumoniae is associated with increased risk of later childhood asthma. We hypothesized that children developing asthma have an abnormal immune response to pathogenic bacteria in infancy. We aimed to assess the bacterial immune response in asymptomatic infants and theassociation with later development of asthma by age 7 years.",

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AU - Larsen, Jeppe Madura

AU - Pedersen, Susanne Brix

AU - Thysen, Anna Hammerich

AU - Birch, S.

AU - Rasmussen, M.A.

AU - Bisgaard, H.

N1 - Conference code: 33

PY - 2014

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N2 - Asthma is a highly prevalent chronic lung disease that commonly originates in early childhood. Colonisation of neonatal airways with the pathogenic bacterial strains H. influenzae, M. catarrhalis and S. pneumoniae is associated with increased risk of later childhood asthma. We hypothesized that children developing asthma have an abnormal immune response to pathogenic bacteria in infancy. We aimed to assess the bacterial immune response in asymptomatic infants and theassociation with later development of asthma by age 7 years.

AB - Asthma is a highly prevalent chronic lung disease that commonly originates in early childhood. Colonisation of neonatal airways with the pathogenic bacterial strains H. influenzae, M. catarrhalis and S. pneumoniae is associated with increased risk of later childhood asthma. We hypothesized that children developing asthma have an abnormal immune response to pathogenic bacteria in infancy. We aimed to assess the bacterial immune response in asymptomatic infants and theassociation with later development of asthma by age 7 years.

M3 - Conference abstract in journal

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VL - 69

SP - 179

EP - 179

JO - Allergy

JF - Allergy

IS - s99

M1 - 404

T2 - European Academy of Allergy and Clinical Immunology Congress 2014

Y2 - 7 June 2014 through 11 June 2014

ER -

Children developing asthma by school-age display aberrant immune responses to pathogenic airway bacteria as infants

Abstract

Conference

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