Children developing asthma by school-age display aberrant immune responses to pathogenic airway bacteria as infants

Jeppe Madura Larsen, Susanne Brix Pedersen, Anna Hammerich Thysen, S. Birch, M.A. Rasmussen, H. Bisgaard

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

    Abstract

    Asthma is a highly prevalent chronic lung disease that commonly originates in early childhood. Colonisation of neonatal airways with the pathogenic bacterial strains H. influenzae, M. catarrhalis and S. pneumoniae is associated with increased risk of later childhood asthma. We hypothesized that children developing asthma have an abnormal immune response to pathogenic bacteria in infancy. We aimed to assess the bacterial immune response in asymptomatic infants and the
    association with later development of asthma by age 7 years.
    Original languageEnglish
    Article number404
    JournalAllergy
    Volume69
    Issue numbers99
    Pages (from-to)179-179
    Number of pages1
    ISSN0105-4538
    Publication statusPublished - 2014
    EventEuropean Academy of Allergy and Clinical Immunology Congress 2014 - Copenhagen, Denmark
    Duration: 7 Jun 201411 Jun 2014

    Conference

    ConferenceEuropean Academy of Allergy and Clinical Immunology Congress 2014
    CountryDenmark
    CityCopenhagen
    Period07/06/201411/06/2014

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