Abstract
The integration of chemistry, biology, and informatics to study drug actions across multiple biological targets, pathways, and biological systems is an emerging paradigm in drug discovery. Rather than
reducing a complex system to simplistic models, fields such as chemogenomics and translational informatics are seeking to build a holistic model for a better understanding of the drug pharmacology and
clinical effects. Here we will present a webserver called ChemProt that can assist, in silico, the drug actions in the context of cellular and disease networks and contribute in the field of disease chemical biology, drug repurposing, and off-target effects prediction.
reducing a complex system to simplistic models, fields such as chemogenomics and translational informatics are seeking to build a holistic model for a better understanding of the drug pharmacology and
clinical effects. Here we will present a webserver called ChemProt that can assist, in silico, the drug actions in the context of cellular and disease networks and contribute in the field of disease chemical biology, drug repurposing, and off-target effects prediction.
| Original language | English |
|---|---|
| Title of host publication | Computational Chemogenomics |
| Publisher | Pan Stanford Publishing |
| Publication date | 2013 |
| Chapter | 7 |
| Publication status | Published - 2013 |