Characterization of a non-fouling ultrafiltration membrane

J. Wei, G.S. Helm, N. Corner-Walker, X. Hou

    Research output: Contribution to journalConference articleResearchpeer-review


    This report describes the properties of surface-modified poly(vinylidene fluoride) (PVDF) membranes. These membranes were created by coating hydrophilic polymers on the support PVDF membrane to reduce the tendency to protein fouling. The modified membranes with different molecular weight cut-off (MWCO) were characterized by filtration studies using bovine serum albumin (BSA) and an enzyme solution as test media, and the membranes exhibited the non-fouling property. The surface chemistry of the unmodified and modified PVDF membranes was characterized by X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectroscopy (ToF-SIMS). These surface sensitive techniques were used to confirm the successful surface modification. ToF-SIMS imaging visualizes the distribution of the coating layer on the PVDF membrane. Furthermore, the amount of protein adsorption onto the membrane surfaces was determined by the radio labeling technique. For the protein adsorption experiments, we have developed a method, which ensures that protein molecules only adsorb on the membrane surface, and that no adsorption on the pore walls of the porous sub-layer takes place.
    Original languageEnglish
    Issue number1-3
    Pages (from-to)252-261
    Publication statusPublished - 2006
    Event2005 International Congress on Membranes and Membrane Processes - Seoul, Korea, Republic of
    Duration: 21 Aug 200526 Aug 2005


    Conference2005 International Congress on Membranes and Membrane Processes
    Country/TerritoryKorea, Republic of


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