Cell motility as persistent random motion: Theories from experiments

D. Selmeczi, S. Mosler, P.H. Hagedorn, N.B. Larsen, H. Flyvbjerg

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Experimental time series for trajectories of motile cells may contain so much information that a systematic analysis will yield cell-type- specific motility models. Here we demonstrate how, using human keratinocytes and fibroblasts as examples. The two resulting models reflect the cells' different roles in the organism, it seems, and show that a cell has a memory of past velocities. They also suggest how to distinguish quantitatively between various surfaces' compatibility with the two cell types.
    Original languageEnglish
    JournalBiophysical Journal
    Volume89
    Issue number2
    Pages (from-to)912-931
    ISSN0006-3495
    DOIs
    Publication statusPublished - Aug 2005

    Keywords

    • BROWNIAN-MOTION
    • ANOMALOUS DIFFUSION
    • MIGRATION
    • LOCOMOTION
    • TISSUE
    • NETWORKS
    • MOVEMENT
    • SURFACES
    • BEHAVIOR
    • BIOLOGY

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