Abstract
Introduction: Diabetes mellitus is an ever-increasing medical condition that currently suffers 1 of 11 adults who may have lifelong commitment with insulin injections. Cell-laden hydrogels releasing insulin may provide the ultimate means of correcting diabetes. Here, we provide insights of this cell-based approach including latest preclinical and clinical progress both from academia and industry.
Area covered: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed.
Expert opinion: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.
Area covered: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed.
Expert opinion: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.
Original language | English |
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Journal | Expert Opinion on Drug Delivery |
Volume | 17 |
Issue number | 8 |
Pages (from-to) | 1113-1118 |
ISSN | 1742-5247 |
DOIs | |
Publication status | Published - 2020 |
Keywords
- Diabetes mellitus
- Cell encapsulation
- Cell-laden hydrogels
- Alginate
- Drug delivery