Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity

Dirk L. Christensen; Daniel Faurholt-Jepsen; Louise Birkegaard; David L Mwaniki; Michael K. Boit; Beatrice Kilonzo; Søren Brage; Henrik Friis; Inge Tetens; Knut Borch-Johnsen; Dorte Vistisen

doi:10.3109/03014460.2015.1013987

Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity

Dirk L. Christensen, Daniel Faurholt-Jepsen, Louise Birkegaard, David L Mwaniki, Michael K. Boit, Beatrice Kilonzo, Søren Brage, Henrik Friis, Inge Tetens, Knut Borch-Johnsen, Dorte Vistisen

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

The relationship between metabolic disease and the non-modifiable risk factors sex, age and ethnicity in Africans is not well-established. This study aimed to describe sex, age and ethnicity differences in blood pressure (BP) and lipid status in rural Kenyans. A cross-sectional study was undertaken among rural Kenyans. BP and pulse rate (PR) were measured while sitting and fasting blood samples were taken for analysis of standard lipid profile. Standard anthropometric measurements were collected. Physical activity energy expenditure was obtained objectively and lifestyle data were obtained using questionnaires. In total, 1139 individuals (61.0% women) participated aged 17-68 years. Age was positively associated with BP and plasma cholesterol levels. Sitting PR was negatively associated with age in women only (sex-interaction p

Original language	English
Journal	Annals of Human Biology
Volume	43
Issue number	1
Pages (from-to)	42-49
Number of pages	8
ISSN	0301-4460
DOIs	https://doi.org/10.3109/03014460.2015.1013987
Publication status	Published - 2016

Keywords

Dyslipidaemia
hypertension
sub-Saharan Africa

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Christensen, D. L., Faurholt-Jepsen, D., Birkegaard, L., Mwaniki, D. L., Boit, M. K., Kilonzo, B., Brage, S., Friis, H., Tetens, I., Borch-Johnsen, K., & Vistisen, D. (2016). Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity. Annals of Human Biology, 43(1), 42-49. https://doi.org/10.3109/03014460.2015.1013987

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title = "Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity",

abstract = "The relationship between metabolic disease and the non-modifiable risk factors sex, age and ethnicity in Africans is not well-established. This study aimed to describe sex, age and ethnicity differences in blood pressure (BP) and lipid status in rural Kenyans. A cross-sectional study was undertaken among rural Kenyans. BP and pulse rate (PR) were measured while sitting and fasting blood samples were taken for analysis of standard lipid profile. Standard anthropometric measurements were collected. Physical activity energy expenditure was obtained objectively and lifestyle data were obtained using questionnaires. In total, 1139 individuals (61.0% women) participated aged 17-68 years. Age was positively associated with BP and plasma cholesterol levels. Sitting PR was negatively associated with age in women only (sex-interaction p ",

keywords = "Dyslipidaemia, hypertension, sub-Saharan Africa",

author = "Christensen, {Dirk L.} and Daniel Faurholt-Jepsen and Louise Birkegaard and Mwaniki, {David L} and Boit, {Michael K.} and Beatrice Kilonzo and S{\o}ren Brage and Henrik Friis and Inge Tetens and Knut Borch-Johnsen and Dorte Vistisen",

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doi = "10.3109/03014460.2015.1013987",

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Christensen, DL, Faurholt-Jepsen, D, Birkegaard, L, Mwaniki, DL, Boit, MK, Kilonzo, B, Brage, S, Friis, H, Tetens, I, Borch-Johnsen, K & Vistisen, D 2016, 'Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity', Annals of Human Biology, vol. 43, no. 1, pp. 42-49. https://doi.org/10.3109/03014460.2015.1013987

TY - JOUR

T1 - Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity

AU - Christensen, Dirk L.

AU - Faurholt-Jepsen, Daniel

AU - Birkegaard, Louise

AU - Mwaniki, David L

AU - Boit, Michael K.

AU - Kilonzo, Beatrice

AU - Brage, Søren

AU - Friis, Henrik

AU - Tetens, Inge

AU - Borch-Johnsen, Knut

AU - Vistisen, Dorte

PY - 2016

Y1 - 2016

N2 - The relationship between metabolic disease and the non-modifiable risk factors sex, age and ethnicity in Africans is not well-established. This study aimed to describe sex, age and ethnicity differences in blood pressure (BP) and lipid status in rural Kenyans. A cross-sectional study was undertaken among rural Kenyans. BP and pulse rate (PR) were measured while sitting and fasting blood samples were taken for analysis of standard lipid profile. Standard anthropometric measurements were collected. Physical activity energy expenditure was obtained objectively and lifestyle data were obtained using questionnaires. In total, 1139 individuals (61.0% women) participated aged 17-68 years. Age was positively associated with BP and plasma cholesterol levels. Sitting PR was negatively associated with age in women only (sex-interaction p

AB - The relationship between metabolic disease and the non-modifiable risk factors sex, age and ethnicity in Africans is not well-established. This study aimed to describe sex, age and ethnicity differences in blood pressure (BP) and lipid status in rural Kenyans. A cross-sectional study was undertaken among rural Kenyans. BP and pulse rate (PR) were measured while sitting and fasting blood samples were taken for analysis of standard lipid profile. Standard anthropometric measurements were collected. Physical activity energy expenditure was obtained objectively and lifestyle data were obtained using questionnaires. In total, 1139 individuals (61.0% women) participated aged 17-68 years. Age was positively associated with BP and plasma cholesterol levels. Sitting PR was negatively associated with age in women only (sex-interaction p

KW - Dyslipidaemia

KW - hypertension

KW - sub-Saharan Africa

U2 - 10.3109/03014460.2015.1013987

DO - 10.3109/03014460.2015.1013987

M3 - Journal article

C2 - 26073640

SN - 0301-4460

VL - 43

SP - 42

EP - 49

JO - Annals of Human Biology

JF - Annals of Human Biology

IS - 1

ER -

Cardiovascular risk factors in rural Kenyans are associated with differential age gradients, but not modified by sex or ethnicity

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Keywords

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