Carbon nanopillars for enhanced stem cell differentiation and dopamine detection

Ada-Ioana Bunea; Letizia Amato; Andrea Valsesia; Paola Pellacani; Andrea Casci Ceccacci; Stephan Sylvest Keller; Niels Bent Larsen; Arto Heiskanen; Jenny Emnéus

Carbon nanopillars for enhanced stem cell differentiation and dopamine detection

Ada-Ioana Bunea, Letizia Amato, Andrea Valsesia, Paola Pellacani, Andrea Casci Ceccacci, Stephan Sylvest Keller, Niels Bent Larsen, Arto Heiskanen, Jenny Emnéus

Center for Intelligent Drug Delivery and Sensing Using Microcontainers and Nanomechanics

European Commission Joint Research Centre Institute

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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Abstract

Parkinson’s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1]. Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine

Original language	English
Publication date	2016
Number of pages	1
Publication status	Published - 2016
Event	Biosensors 2016: 26th Anniversary World Congress on Biosensors - Swedish Exhibition and Congress Centre, Gothenburg, Sweden Duration: 25 May 2016 → 27 May 2016 Conference number: 26 http://www.biosensors-congress.elsevier.com/

Conference

Conference	Biosensors 2016
Number	26
Location	Swedish Exhibition and Congress Centre
Country/Territory	Sweden
City	Gothenburg
Period	25/05/2016 → 27/05/2016
Internet address	http://www.biosensors-congress.elsevier.com/

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title = "Carbon nanopillars for enhanced stem cell differentiation and dopamine detection",

abstract = "Parkinson{\textquoteright}s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1]. Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine",

author = "Ada-Ioana Bunea and Letizia Amato and Andrea Valsesia and Paola Pellacani and {Casci Ceccacci}, Andrea and Keller, {Stephan Sylvest} and Larsen, {Niels Bent} and Arto Heiskanen and Jenny Emn{\'e}us",

year = "2016",

language = "English",

note = "Biosensors 2016 : 26th Anniversary World Congress on Biosensors ; Conference date: 25-05-2016 Through 27-05-2016",

url = "http://www.biosensors-congress.elsevier.com/",

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TY - ABST

T1 - Carbon nanopillars for enhanced stem cell differentiation and dopamine detection

AU - Bunea, Ada-Ioana

AU - Amato, Letizia

AU - Valsesia, Andrea

AU - Pellacani, Paola

AU - Casci Ceccacci, Andrea

AU - Keller, Stephan Sylvest

AU - Larsen, Niels Bent

AU - Heiskanen, Arto

AU - Emnéus, Jenny

N1 - Conference code: 26

PY - 2016

Y1 - 2016

N2 - Parkinson’s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1]. Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine

AB - Parkinson’s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1]. Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine

M3 - Conference abstract for conference

T2 - Biosensors 2016

Y2 - 25 May 2016 through 27 May 2016

ER -

Carbon nanopillars for enhanced stem cell differentiation and dopamine detection

Abstract

Conference

UN SDGs

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