Carbon nanopillars for enhanced stem cell differentiation and dopamine detection

Ada-Ioana Bunea, Letizia Amato, Andrea Valsesia, Paola Pellacani, Andrea Casci Ceccacci, Stephan Sylvest Keller, Niels Bent Larsen, Arto Heiskanen, Jenny Emnéus

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    Abstract

    Parkinson’s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1]. Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine
    Original languageEnglish
    Publication date2016
    Number of pages1
    Publication statusPublished - 2016
    EventBiosensors 2016: 26th Anniversary World Congress on Biosensors - Swedish Exhibition and Congress Centre, Gothenburg, Sweden
    Duration: 25 May 201627 May 2016
    Conference number: 26
    http://www.biosensors-congress.elsevier.com/

    Conference

    ConferenceBiosensors 2016
    Number26
    LocationSwedish Exhibition and Congress Centre
    Country/TerritorySweden
    CityGothenburg
    Period25/05/201627/05/2016
    Internet address

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