Carbon nanopillars for enhanced stem cell differentiation and dopamine detection

Ada-Ioana Bunea, Letizia Amato, Andrea Valsesia, Paola Pellacani, Andrea Casci Ceccacci, Stephan Sylvest Keller, Niels Bent Larsen, Arto Heiskanen, Jenny Emnéus

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Abstract

Parkinson’s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1]. Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine
Original languageEnglish
Publication date2016
Number of pages1
Publication statusPublished - 2016
EventBiosensors 2016: 26th Anniversary World Congress on Biosensors - Swedish Exhibition and Congress Centre, Gothenburg, Sweden
Duration: 25 May 201627 May 2016
Conference number: 26
http://www.biosensors-congress.elsevier.com/

Conference

ConferenceBiosensors 2016
Number26
LocationSwedish Exhibition and Congress Centre
CountrySweden
CityGothenburg
Period25/05/201627/05/2016
Internet address

Cite this

Bunea, A-I., Amato, L., Valsesia, A., Pellacani, P., Casci Ceccacci, A., Keller, S. S., Larsen, N. B., Heiskanen, A., & Emnéus, J. (2016). Carbon nanopillars for enhanced stem cell differentiation and dopamine detection. Abstract from Biosensors 2016, Gothenburg, Sweden.