Cantilever-Based Microwave Biosensors: Analysis, Designs and Optimizations

Chenhui Jiang; Tom Keinicke Johansen; Sævar Þór Jónasson; Lei Yan; Anja Boisen

Cantilever-Based Microwave Biosensors: Analysis, Designs and Optimizations

Chenhui Jiang, Tom Keinicke Johansen, Sævar Þór Jónasson, Lei Yan, Anja Boisen

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

This paper presents a novel microwave readout scheme for measuring deflection of cantilevers in nanometer range. The cantilever deflection can be sensed by the variation of transmission levels or resonant frequencies of microwave signals. The sensitivity of the cantilever biosensor based on LC resonators is at first theoretically analyzed. A LC resonator based biosensor with beams is designed and optimized by using 3D electromagnetic (EM) simulations, where the beam is a typical variation of cantilevers. The sensitivity of the lossless biosensor is predicted as 4.6MHz/nm. The 3-dB bandwidths of the resonances are narrowed for improving the resolution of distinguishing resonances by reducing conductive loss of electrodes. The lossy biosensor can achieve the highest sensitivity as 5.6 MHz/nm and narrowest 3-dB bandwidth as 5 GHz.

Original language	English
Title of host publication	Proceedings of the 27th Annual Review of Progress in Applied Computational Electromagnetics
Publication date	2011
Publication status	Published - 2011
Event	27th Annual Review of Progress in Applied Computational Electromagnetics - Williamsburg, United States Duration: 27 Mar 2011 → 31 Mar 2011

Conference

Conference	27th Annual Review of Progress in Applied Computational Electromagnetics
Country/Territory	United States
City	Williamsburg
Period	27/03/2011 → 31/03/2011

Keywords

LC resonators
Microwave biosensors
Cantilevers
Electromagnetic simulations
Beams

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@inproceedings{4d434286790c483e9854ec0534a72035,

title = "Cantilever-Based Microwave Biosensors: Analysis, Designs and Optimizations",

abstract = "This paper presents a novel microwave readout scheme for measuring deflection of cantilevers in nanometer range. The cantilever deflection can be sensed by the variation of transmission levels or resonant frequencies of microwave signals. The sensitivity of the cantilever biosensor based on LC resonators is at first theoretically analyzed. A LC resonator based biosensor with beams is designed and optimized by using 3D electromagnetic (EM) simulations, where the beam is a typical variation of cantilevers. The sensitivity of the lossless biosensor is predicted as 4.6MHz/nm. The 3-dB bandwidths of the resonances are narrowed for improving the resolution of distinguishing resonances by reducing conductive loss of electrodes. The lossy biosensor can achieve the highest sensitivity as 5.6 MHz/nm and narrowest 3-dB bandwidth as 5 GHz.",

keywords = "LC resonators, Microwave biosensors, Cantilevers, Electromagnetic simulations, Beams",

author = "Chenhui Jiang and Johansen, {Tom Keinicke} and J{\'o}nasson, {S{\ae}var {\TH}{\'o}r} and Lei Yan and Anja Boisen",

year = "2011",

language = "English",

booktitle = "Proceedings of the 27th Annual Review of Progress in Applied Computational Electromagnetics",

note = "27th Annual Review of Progress in Applied Computational Electromagnetics, ACES 2011 ; Conference date: 27-03-2011 Through 31-03-2011",

}

TY - GEN

T1 - Cantilever-Based Microwave Biosensors: Analysis, Designs and Optimizations

AU - Jiang, Chenhui

AU - Johansen, Tom Keinicke

AU - Jónasson, Sævar Þór

AU - Yan, Lei

AU - Boisen, Anja

PY - 2011

Y1 - 2011

N2 - This paper presents a novel microwave readout scheme for measuring deflection of cantilevers in nanometer range. The cantilever deflection can be sensed by the variation of transmission levels or resonant frequencies of microwave signals. The sensitivity of the cantilever biosensor based on LC resonators is at first theoretically analyzed. A LC resonator based biosensor with beams is designed and optimized by using 3D electromagnetic (EM) simulations, where the beam is a typical variation of cantilevers. The sensitivity of the lossless biosensor is predicted as 4.6MHz/nm. The 3-dB bandwidths of the resonances are narrowed for improving the resolution of distinguishing resonances by reducing conductive loss of electrodes. The lossy biosensor can achieve the highest sensitivity as 5.6 MHz/nm and narrowest 3-dB bandwidth as 5 GHz.

AB - This paper presents a novel microwave readout scheme for measuring deflection of cantilevers in nanometer range. The cantilever deflection can be sensed by the variation of transmission levels or resonant frequencies of microwave signals. The sensitivity of the cantilever biosensor based on LC resonators is at first theoretically analyzed. A LC resonator based biosensor with beams is designed and optimized by using 3D electromagnetic (EM) simulations, where the beam is a typical variation of cantilevers. The sensitivity of the lossless biosensor is predicted as 4.6MHz/nm. The 3-dB bandwidths of the resonances are narrowed for improving the resolution of distinguishing resonances by reducing conductive loss of electrodes. The lossy biosensor can achieve the highest sensitivity as 5.6 MHz/nm and narrowest 3-dB bandwidth as 5 GHz.

KW - LC resonators

KW - Microwave biosensors

KW - Cantilevers

KW - Electromagnetic simulations

KW - Beams

M3 - Article in proceedings

BT - Proceedings of the 27th Annual Review of Progress in Applied Computational Electromagnetics

T2 - 27th Annual Review of Progress in Applied Computational Electromagnetics

Y2 - 27 March 2011 through 31 March 2011

ER -

Cantilever-Based Microwave Biosensors: Analysis, Designs and Optimizations

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Keywords

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