Cancer diagnosis, treatment selection and treatment

Zoltan I Szallasi; Andrea L Richardson; Nicolai J Birkbak; Zhigang Wang

Cancer diagnosis, treatment selection and treatment

Zoltan I Szallasi (Inventor), Andrea L Richardson (Inventor), Nicolai J Birkbak (Inventor), Zhigang Wang (Inventor)

Department of Biotechnology and Biomedicine

Research output: Patent

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Abstract

The present invention provides assays, methods and systems for selecting an effective therapy for a subset of cancer patients having cancer cells with increased expression of BML and FANCI genes and/or having copy number increase in chromosome location 15q26 in the cancer cells and for treatment of such patients with the effective therapy of cancer patients based on the personalized cancer cell expression profile.

Original language	English
IPC	G01N 33/ 15 A I
Patent number	WO2014160080
Filing date	13/03/2013
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	14/03/2013
Priority number	US201361784234P
Publication status	Published - 2 Oct 2014

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abstract = "The present invention provides assays, methods and systems for selecting an effective therapy for a subset of cancer patients having cancer cells with increased expression of BML and FANCI genes and/or having copy number increase in chromosome location 15q26 in the cancer cells and for treatment of such patients with the effective therapy of cancer patients based on the personalized cancer cell expression profile.",

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N2 - The present invention provides assays, methods and systems for selecting an effective therapy for a subset of cancer patients having cancer cells with increased expression of BML and FANCI genes and/or having copy number increase in chromosome location 15q26 in the cancer cells and for treatment of such patients with the effective therapy of cancer patients based on the personalized cancer cell expression profile.

AB - The present invention provides assays, methods and systems for selecting an effective therapy for a subset of cancer patients having cancer cells with increased expression of BML and FANCI genes and/or having copy number increase in chromosome location 15q26 in the cancer cells and for treatment of such patients with the effective therapy of cancer patients based on the personalized cancer cell expression profile.

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Cancer diagnosis, treatment selection and treatment

Abstract

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