Abstract
We investigated the use of a simple calibration method to remove bias in previously proposed approaches to image-derived input functions (IDIFs) when used to calculate the metabolic uptake rate of glucose (Km) from dynamic [18F]-FDG PET scans of the thigh. Our objective was to obtain nonbiased, low-variance Km values without blood sampling.
Original language | English |
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Journal | Nuclear Medicine Communications |
Volume | 35 |
Issue number | 4 |
Pages (from-to) | 353-361 |
ISSN | 0143-3636 |
DOIs | |
Publication status | Published - 2014 |
Keywords
- calibration
- image-derived input function
- kinetic analysis
- positron emission tomography