Burst pressure of phaseguide structures of different heights in all-polymer microfluidic channels

Francesca Garbarino, Kasper Kistrup, Giovanni Rizzi, Mikkel Fougt Hansen

    Research output: Contribution to journalJournal articleResearchpeer-review

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    Abstract

    We present an experimental investigation of the burst/overflow pressure of water and a representative surfactant-containing buffer in microfluidic channels with phaseguide structures oriented at an angle of 90° to the channel length as a function of their height, . The all-polymer chips were fabricated by injection moulding and sealed by ultrasonic welding. Channels with a height of 200 m and widths of 1 mm or 3 mm were investigated for five values of between 8 m and 82 m. Phaseguide structures without branches and with branches at angles = 45°, 60° and 75° were studied. All phaseguide structures were found able to pin both liquids and the burst pressure was found to increase approximately linearly with the height of the phaseguide from about 100–350 Pa for water and from about 25–200 Pa for the buffer. The burst pressure was found not to depend on the channel width and it was only weakly influenced by the presence of a branch on the phaseguide. For phaseguides with a branch, the liquid was always found to burst at the branch location. The measured burst pressures were compared to those estimated using a simple theory. The knowledge obtained in this study enables simple tuning of liquid spreading and overflow in microfluidic channels by use of phaseguide structures with different heights and it also provides a set of systematic experimental data to be compared with simulations/theory.
    Original languageEnglish
    Article number125015
    JournalJournal of Micromechanics and Microengineering
    Volume27
    Issue number12
    Number of pages9
    ISSN0960-1317
    DOIs
    Publication statusPublished - 2017

    Keywords

    • All-polymer chip
    • Phaseguide
    • Injection moulding
    • Ultrasonic welding
    • Hydrostatic burst pressure
    • Topas

    Cite this

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    title = "Burst pressure of phaseguide structures of different heights in all-polymer microfluidic channels",
    abstract = "We present an experimental investigation of the burst/overflow pressure of water and a representative surfactant-containing buffer in microfluidic channels with phaseguide structures oriented at an angle of 90° to the channel length as a function of their height, . The all-polymer chips were fabricated by injection moulding and sealed by ultrasonic welding. Channels with a height of 200 m and widths of 1 mm or 3 mm were investigated for five values of between 8 m and 82 m. Phaseguide structures without branches and with branches at angles = 45°, 60° and 75° were studied. All phaseguide structures were found able to pin both liquids and the burst pressure was found to increase approximately linearly with the height of the phaseguide from about 100–350 Pa for water and from about 25–200 Pa for the buffer. The burst pressure was found not to depend on the channel width and it was only weakly influenced by the presence of a branch on the phaseguide. For phaseguides with a branch, the liquid was always found to burst at the branch location. The measured burst pressures were compared to those estimated using a simple theory. The knowledge obtained in this study enables simple tuning of liquid spreading and overflow in microfluidic channels by use of phaseguide structures with different heights and it also provides a set of systematic experimental data to be compared with simulations/theory.",
    keywords = "All-polymer chip, Phaseguide, Injection moulding, Ultrasonic welding, Hydrostatic burst pressure, Topas",
    author = "Francesca Garbarino and Kasper Kistrup and Giovanni Rizzi and Hansen, {Mikkel Fougt}",
    year = "2017",
    doi = "10.1088/1361-6439/aa97b7",
    language = "English",
    volume = "27",
    journal = "Journal of Micromechanics and Microengineering",
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    Burst pressure of phaseguide structures of different heights in all-polymer microfluidic channels. / Garbarino, Francesca; Kistrup, Kasper; Rizzi, Giovanni; Hansen, Mikkel Fougt.

    In: Journal of Micromechanics and Microengineering, Vol. 27, No. 12, 125015, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

    TY - JOUR

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    AU - Kistrup, Kasper

    AU - Rizzi, Giovanni

    AU - Hansen, Mikkel Fougt

    PY - 2017

    Y1 - 2017

    N2 - We present an experimental investigation of the burst/overflow pressure of water and a representative surfactant-containing buffer in microfluidic channels with phaseguide structures oriented at an angle of 90° to the channel length as a function of their height, . The all-polymer chips were fabricated by injection moulding and sealed by ultrasonic welding. Channels with a height of 200 m and widths of 1 mm or 3 mm were investigated for five values of between 8 m and 82 m. Phaseguide structures without branches and with branches at angles = 45°, 60° and 75° were studied. All phaseguide structures were found able to pin both liquids and the burst pressure was found to increase approximately linearly with the height of the phaseguide from about 100–350 Pa for water and from about 25–200 Pa for the buffer. The burst pressure was found not to depend on the channel width and it was only weakly influenced by the presence of a branch on the phaseguide. For phaseguides with a branch, the liquid was always found to burst at the branch location. The measured burst pressures were compared to those estimated using a simple theory. The knowledge obtained in this study enables simple tuning of liquid spreading and overflow in microfluidic channels by use of phaseguide structures with different heights and it also provides a set of systematic experimental data to be compared with simulations/theory.

    AB - We present an experimental investigation of the burst/overflow pressure of water and a representative surfactant-containing buffer in microfluidic channels with phaseguide structures oriented at an angle of 90° to the channel length as a function of their height, . The all-polymer chips were fabricated by injection moulding and sealed by ultrasonic welding. Channels with a height of 200 m and widths of 1 mm or 3 mm were investigated for five values of between 8 m and 82 m. Phaseguide structures without branches and with branches at angles = 45°, 60° and 75° were studied. All phaseguide structures were found able to pin both liquids and the burst pressure was found to increase approximately linearly with the height of the phaseguide from about 100–350 Pa for water and from about 25–200 Pa for the buffer. The burst pressure was found not to depend on the channel width and it was only weakly influenced by the presence of a branch on the phaseguide. For phaseguides with a branch, the liquid was always found to burst at the branch location. The measured burst pressures were compared to those estimated using a simple theory. The knowledge obtained in this study enables simple tuning of liquid spreading and overflow in microfluidic channels by use of phaseguide structures with different heights and it also provides a set of systematic experimental data to be compared with simulations/theory.

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    KW - Phaseguide

    KW - Injection moulding

    KW - Ultrasonic welding

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    KW - Topas

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    JF - Journal of Micromechanics and Microengineering

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