Burden-addicted production strains

Peter Rugbjerg (Inventor), William Kristian Pallisgaard Olsen (Inventor), Morten Otto Alexander Sommer (Inventor), Anne Line Tidemand Johansen (Inventor)

Research output: Patent

32 Downloads (Pure)


The invention provides a microbial production cell for synthesis of a product, further comprising a burden-addiction genetic circuit whose expression confers a selective growth and/or survival advantage on those cells that synthesize the product; while limiting proliferation of low- or non-productive escaper cells.

Original languageEnglish
IPCC12P 21/ 00 A I
Patent numberWO2021160854
Filing date12/02/2021
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date13/02/2020
Priority numberEP20200157159
Publication statusPublished - 19 Aug 2021


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