Brewer’s spent grain as raw material for lactic acid production by Lactobacillus delbrueckii

Solange I. Mussatto, Marcela Fernandes, Giuliano Dragone, Ismael M. Mancilha, Inês Conceicao Roberto

Research output: Contribution to journalJournal articleResearchpeer-review


Chemically pre-treated brewer’s spent grain was saccharified with cellulase producing a hydrolysate with approx. 50 g glucose l−1. This hydrolysate was used as a fermentation medium without any nutrient supplementation by Lactobacillus delbrueckii, which produced L-lactic acid (5.4 g l−1) at 0.73 g g−1 glucose consumed (73% efficiency). An inoculum of 1 g dry cells l−1 gave the best yield of the process, but the pH decrease affected the microorganism capacity to consume glucose and convert it into lactic acid.
Original languageEnglish
JournalBiotechnology Letters
Issue number12
Pages (from-to)1973-1976
Publication statusPublished - 2007
Externally publishedYes

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