Biotechnology for renewable chemicals

Irina Borodina, Kanchana Rueksomtawin Kildegaard, Niels Bjerg Jensen, Svetlana Sherstyk, Jerome Maury, Jochen Forster, Markus Herrgard, Jens Nielsen

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review


The majority of the industrial organic chemicals are derived from fossil sources. With the oil and gas resources becoming limiting, biotechnology offers a sustainable alternative for production ofchemicals from renewable feedstocks. Yeast is an attractive cell factory forsustainable production of chemicals, due to its safe use status, tolerance of low pH and inhibitors, and amenability to large-scale fermentations. There are examples of commercial processes for production of organic acids such aslactic and succinic acids in yeast. We have engineered baker’s yeast Saccharomyces cerevisiae for the production of non-native 3-hydroxypropionic acid (3HP).3HP can be chemically dehydrated into acrylic acid and thus can serve as a biosustainable building block for acrylate-based products (diapers, acrylic paints, acrylic polymers, etc.)
Original languageEnglish
Title of host publicationAbstract Book - DTU Sustain Conference 2014
Number of pages1
Place of PublicationKgs. Lyngby
PublisherTechnical University of Denmark
Publication date2014
Publication statusPublished - 2014
EventDTU Sustain Conference 2014 - Technical University of Denmark, Lyngby, Denmark
Duration: 17 Dec 201417 Dec 2014


ConferenceDTU Sustain Conference 2014
LocationTechnical University of Denmark
Internet address


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