Biosynthesis of forskolin and related compounds

Björn Hamberger; Birger Lindberg Møller; Eirini Pateraki; Johan Andersen Ranberg; Niels Bjerg Jensen

Biosynthesis of forskolin and related compounds

Björn Hamberger (Inventor)
, Birger Lindberg Møller (Inventor)
, Eirini Pateraki (Inventor)
, Johan Andersen Ranberg (Inventor)
, Niels Bjerg Jensen (Inventor)

Research output: Patent

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Abstract

The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R- MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.

Original language	English
IPC	C12P 17/ 06 A I
Patent number	WO2015113569
Filing date	06/08/2016
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	03/09/2014
Priority number	DK20140070536
Publication status	Published - 6 Aug 2015

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title = "Biosynthesis of forskolin and related compounds",

abstract = "The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R- MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.",

author = "Bj{\"o}rn Hamberger and M{\o}ller, \{Birger Lindberg\} and Eirini Pateraki and Ranberg, \{Johan Andersen\} and Jensen, \{Niels Bjerg\}",

year = "2015",

month = aug,

day = "6",

language = "English",

type = "Patent",

note = "WO2015113569; C12P 17/ 06 A I",

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TY - PAT

T1 - Biosynthesis of forskolin and related compounds

AU - Hamberger, Björn

AU - Møller, Birger Lindberg

AU - Pateraki, Eirini

AU - Ranberg, Johan Andersen

AU - Jensen, Niels Bjerg

PY - 2015/8/6

Y1 - 2015/8/6

N2 - The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R- MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.

AB - The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R- MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.

M3 - Patent

M1 - WO2015113569

Y2 - 2016/08/06

ER -

Biosynthesis of forskolin and related compounds

Abstract

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