Abstract
The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R- MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.
Original language | English |
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IPC | C12P 17/ 06 A I |
Patent number | WO2015113569 |
Filing date | 06/08/2016 |
Country | International Bureau of the World Intellectual Property Organization (WIPO) |
Priority date | 03/09/2014 |
Priority number | DK20140070536 |
Publication status | Published - 6 Aug 2015 |