Biosynthesis of forskolin and related compounds

Björn Hamberger (Inventor), Birger Lindberg Møller (Inventor), Eirini Pateraki (Inventor), Johan Andersen Ranberg (Inventor), Niels Bjerg Jensen (Inventor)

Research output: Patent

116 Downloads (Pure)

Abstract

The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R- MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.

Original languageEnglish
IPCC12P 17/ 06 A I
Patent numberWO2015113569
Filing date06/08/2016
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date03/09/2014
Priority numberDK20140070536
Publication statusPublished - 6 Aug 2015

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