Biological production of polyhydroxyalkanoates and monomers therefor using engineered pseudomonas cells

Pablo Nikel; Nicolás Gurdo; Mariela Paula Mezzina; Nicolas Krink; Tommaso Tagliani; Alberto De Maria

Biological production of polyhydroxyalkanoates and monomers therefor using engineered pseudomonas cells

Pablo Nikel (Inventor), Nicolás Gurdo (Inventor), Mariela Paula Mezzina (Inventor), Nicolas Krink (Inventor), Tommaso Tagliani (Inventor), Alberto De Maria (Inventor)

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Abstract

The present invention relates to cells and methods for producing polymers from acetate. The invention also relates to cells with increased tolerance to short-chain organic acids, such as acetate. In particular, the invention relates to production of polyhydroxybutyrate (PHB), fluorinated 3-hydroxybutyrate and fluorinated PHB (F-PHB) from acetate and/or F-acetate using bacterial cells with increased tolerance to acetate.

Original language	English
IPC	C12P 7/ 625 A I
Patent number	WO2025051835
Filing date	05/09/2024
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	06/09/2023
Priority number	EP20230195846
Publication status	Published - 2025

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title = "Biological production of polyhydroxyalkanoates and monomers therefor using engineered pseudomonas cells",

abstract = "The present invention relates to cells and methods for producing polymers from acetate. The invention also relates to cells with increased tolerance to short-chain organic acids, such as acetate. In particular, the invention relates to production of polyhydroxybutyrate (PHB), fluorinated 3-hydroxybutyrate and fluorinated PHB (F-PHB) from acetate and/or F-acetate using bacterial cells with increased tolerance to acetate.",

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TY - PAT

T1 - Biological production of polyhydroxyalkanoates and monomers therefor using engineered pseudomonas cells

AU - Nikel, Pablo

AU - Gurdo, Nicolás

AU - Mezzina, Mariela Paula

AU - Krink, Nicolas

AU - Tagliani, Tommaso

AU - De Maria, Alberto

PY - 2025

Y1 - 2025

N2 - The present invention relates to cells and methods for producing polymers from acetate. The invention also relates to cells with increased tolerance to short-chain organic acids, such as acetate. In particular, the invention relates to production of polyhydroxybutyrate (PHB), fluorinated 3-hydroxybutyrate and fluorinated PHB (F-PHB) from acetate and/or F-acetate using bacterial cells with increased tolerance to acetate.

AB - The present invention relates to cells and methods for producing polymers from acetate. The invention also relates to cells with increased tolerance to short-chain organic acids, such as acetate. In particular, the invention relates to production of polyhydroxybutyrate (PHB), fluorinated 3-hydroxybutyrate and fluorinated PHB (F-PHB) from acetate and/or F-acetate using bacterial cells with increased tolerance to acetate.

M3 - Patent

M1 - WO2025051835

Y2 - 2024/09/05

ER -

Biological production of polyhydroxyalkanoates and monomers therefor using engineered pseudomonas cells

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