Bioimpedance measurements on human neural stem cells as a benchmark for the development of smart mobile biomedical applications

André B. Cunha, Christin Schuelke, Arto Heiskanen, Afia Asif, Yasmin Mohamed Hassan, Stephan Sylvest Keller, Håvard Kalvøy, Alberto Martínez-Serrano, Jenny Emnéus, Ørjan G. Martinsen

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Abstract

Over the past 30 years, stem cell technologies matured from an attractive option to investigate neurodegenerative diseases to a possible paradigm shift in their treatment through the development of cell-based regenerative medicine (CRM). Implantable cell replacement therapies promise to completely restore function of neural structures possibly changing how we currently perceive the onset of these conditions. One of the major clinical hurdles facing the routine implementation of stem cell therapy is the limited and inconsistent benefit observed thus far. While unclear, numerous pre-clinical and a handful of clinical cell fate imaging studies point to poor cell retention and survival. Coupling the need to better understand these mechanisms while providing scalable approaches to monitor these treatments in both pre-clinical and clinical scenarios, we show a proof of concept bioimpedance electronic platform for the Agile development of smart and mobile biomedical applications like neural implants or highly portable monitoring devices.
Original languageEnglish
Title of host publicationProceedings of the International Conference on Electrical Bioimpedance (ICEBI2019)
Number of pages11
Publication date2019
DOIs
Publication statusPublished - 2019
EventXVII International Conference on Electrical Bioimpedance (ICEBI 2019) - Joinville, Santa Catarina, Brazil
Duration: 9 Jun 201913 Jun 2019
Conference number: 17
http://icebi2019.joinville.br/

Conference

ConferenceXVII International Conference on Electrical Bioimpedance (ICEBI 2019)
Number17
LocationJoinville
CountryBrazil
CitySanta Catarina
Period09/06/201913/06/2019
Internet address

Keywords

  • Electrical Impedance Spectroscopy (EIS)
  • Bioimpedance
  • Neural Stem Cells (NSCs)
  • Proliferation
  • Embedded System
  • Mobile Technologies

Cite this

Cunha, A. B., Schuelke, C., Heiskanen, A., Asif, A., Hassan, Y. M., Keller, S. S., ... Martinsen, Ø. G. (2019). Bioimpedance measurements on human neural stem cells as a benchmark for the development of smart mobile biomedical applications. In Proceedings of the International Conference on Electrical Bioimpedance (ICEBI2019) https://doi.org/10.29007/4b1g