Biofilm formation by asymptomatic and virulent urinary tract infectious Escherichia coli strains

Viktoria Hancock, Lionel Ferrieres, Per Klemm

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Escherichia coli is the most common organism associated with asymptomatic bacteriuria (ABU) in humans. In contrast to uropathogenic E. coli (UPEC) that cause symptomatic urinary tract infection, very little is known about the mechanisms by which these strains colonize the urinary tract. Here, we have investigated the biofilm-forming capacity on abiotic surfaces of groups of ABU strains and UPEC strains in human urine. We found that there is a strong bias; ABU strains were significantly better biofilm formers than UPEC strains. Our data suggest that biofilm formation in urinary tract infectious E. coli seems to be associated with ABU strains and appears to be an important strategy used by these strains for persistence in this high-flow environment.
    Original languageEnglish
    JournalF E M S Microbiology Letters
    Volume267
    Issue number1
    Pages (from-to)30-37
    ISSN0378-1097
    DOIs
    Publication statusPublished - 2007

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