Bio-optofluidics and biophotonics at the cellular level

Andrew Rafael Bañas; Darwin Palima; Sandeep Tauro; Finn Pedersen; Jesper Glückstad

Bio-optofluidics and biophotonics at the cellular level

Andrew Rafael Bañas
, Darwin Palima
, Sandeep Tauro
, Finn Pedersen
, Jesper Glückstad

Research output: Contribution to journal › Journal article › Research

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Abstract

We present ongoing research and development activities for constructing a compact next generation BioPhotonics
Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micro-manipulation platforms utilizing low numerical
aperture beam geometries. Unlike conventional high NA optical tweezers, the BioPhotonics workstation is e.g.
capable of long range 3D manipulation. This enables a variety of biological studies such as manipulation of intricate microfabricated
assemblies or for automated and parallel optofluidic cell sorting. To further reduce its overhead, we propose
ways of making the BioPhotonics Workstation platform more photon efficient by studying the 3D distribution of the counter
propagating beams and utilizing the Generalized Phase Contrast (GPC) method for illuminating the applied spatial light
modulators. Moving ahead, we envision optimal designs for the manipulated microstructures through the use of advanced
topology optimization.

Original language	English
Journal	DOPS-Nyt
Volume	26
Issue number	1
Pages (from-to)	4-9
Publication status	Published - 2012

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abstract = "We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micro-manipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optical tweezers, the BioPhotonics workstation is e.g. capable of long range 3D manipulation. This enables a variety of biological studies such as manipulation of intricate microfabricated assemblies or for automated and parallel optofluidic cell sorting. To further reduce its overhead, we propose ways of making the BioPhotonics Workstation platform more photon efficient by studying the 3D distribution of the counter propagating beams and utilizing the Generalized Phase Contrast (GPC) method for illuminating the applied spatial light modulators. Moving ahead, we envision optimal designs for the manipulated microstructures through the use of advanced topology optimization.",

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AU - Bañas, Andrew Rafael

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AU - Tauro, Sandeep

AU - Pedersen, Finn

AU - Glückstad, Jesper

PY - 2012

Y1 - 2012

N2 - We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micro-manipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optical tweezers, the BioPhotonics workstation is e.g. capable of long range 3D manipulation. This enables a variety of biological studies such as manipulation of intricate microfabricated assemblies or for automated and parallel optofluidic cell sorting. To further reduce its overhead, we propose ways of making the BioPhotonics Workstation platform more photon efficient by studying the 3D distribution of the counter propagating beams and utilizing the Generalized Phase Contrast (GPC) method for illuminating the applied spatial light modulators. Moving ahead, we envision optimal designs for the manipulated microstructures through the use of advanced topology optimization.

AB - We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micro-manipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optical tweezers, the BioPhotonics workstation is e.g. capable of long range 3D manipulation. This enables a variety of biological studies such as manipulation of intricate microfabricated assemblies or for automated and parallel optofluidic cell sorting. To further reduce its overhead, we propose ways of making the BioPhotonics Workstation platform more photon efficient by studying the 3D distribution of the counter propagating beams and utilizing the Generalized Phase Contrast (GPC) method for illuminating the applied spatial light modulators. Moving ahead, we envision optimal designs for the manipulated microstructures through the use of advanced topology optimization.

M3 - Journal article

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EP - 9

JO - DOPS-Nyt

JF - DOPS-Nyt

IS - 1

ER -

Bio-optofluidics and biophotonics at the cellular level

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