The individual functional unit of the kidney (the nephron) displays oscillations in its pressure and flow regulation at two different time scales: fast oscillations associated with a myogenic dynamics of the afferent arteriole, and slower oscillations arising from a delay in the tubuloglomerular feedback. We investigate the intra- and internephron entrainment of the two time scales. In addition to full synchronization, both wavelet analyses of experimental data and numerical simulations reveal a partial entrainment in which neighboring nephrons attain a state of chaotic synchronization with respect to their slow dynamics, but the fast dynamics remain desynchronized.
|Journal||Physical Review E. Statistical, Nonlinear, and Soft Matter Physics|
|Publication status||Published - 2002|
Bibliographical noteCopyright (2002) American Physical Society
- SPONTANEOUSLY HYPERTENSIVE RATS
- TUBULOGLOMERULAR FEEDBACK
- FLOW REGULATION