Bead Capture and Release on a Magnetic Sensor in a Microfluidic System

Bjarke Thomas Dalslet; Christian Danvad Damsgaard; S.C. Freitas; P.P. Freitas; Mikkel Fougt Hansen

doi:10.1109/ICSENS.2008.4716426

Bead Capture and Release on a Magnetic Sensor in a Microfluidic System

Bjarke Thomas Dalslet, Christian Danvad Damsgaard, S.C. Freitas, P.P. Freitas, Mikkel Fougt Hansen

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Abstract

Planar Hall effect magnetic sensors for detection of biological agents using surface treated magnetic beads are integrated with a fluid injection system. The response of the sensors is used to evaluate bead capture rates for different bead concentrations c and fluid flow rates Q, and to monitor subsequent removal of the beads. It is found that the capture rate scales directly with c and that it depends linearly on Q. At low Q the capture rate is only partially due to gravitational sedimentation of beads. At higher Q an additional term proportional to Q becomes important, which is attributed to capture of beads by the magnetic fields near the sensor. It is shown that beads can be washed off the sensor surface.

Original language	English
Publication date	2008
DOIs	https://doi.org/10.1109/ICSENS.2008.4716426
Publication status	Published - 2008
Event	2008 IEEE Sensors - Lecce, Italy Duration: 26 Oct 2008 → 29 Oct 2008 http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=4703548

Conference

Conference	2008 IEEE Sensors
Country/Territory	Italy
City	Lecce
Period	26/10/2008 → 29/10/2008
Internet address	http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=4703548

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Copyright: 2008 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE

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title = "Bead Capture and Release on a Magnetic Sensor in a Microfluidic System",

abstract = "Planar Hall effect magnetic sensors for detection of biological agents using surface treated magnetic beads are integrated with a fluid injection system. The response of the sensors is used to evaluate bead capture rates for different bead concentrations c and fluid flow rates Q, and to monitor subsequent removal of the beads. It is found that the capture rate scales directly with c and that it depends linearly on Q. At low Q the capture rate is only partially due to gravitational sedimentation of beads. At higher Q an additional term proportional to Q becomes important, which is attributed to capture of beads by the magnetic fields near the sensor. It is shown that beads can be washed off the sensor surface.",

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note = "Copyright: 2008 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE; 2008 IEEE Sensors ; Conference date: 26-10-2008 Through 29-10-2008",

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AU - Dalslet, Bjarke Thomas

AU - Damsgaard, Christian Danvad

AU - Freitas, S.C.

AU - Freitas, P.P.

AU - Hansen, Mikkel Fougt

N1 - Copyright: 2008 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE

PY - 2008

Y1 - 2008

N2 - Planar Hall effect magnetic sensors for detection of biological agents using surface treated magnetic beads are integrated with a fluid injection system. The response of the sensors is used to evaluate bead capture rates for different bead concentrations c and fluid flow rates Q, and to monitor subsequent removal of the beads. It is found that the capture rate scales directly with c and that it depends linearly on Q. At low Q the capture rate is only partially due to gravitational sedimentation of beads. At higher Q an additional term proportional to Q becomes important, which is attributed to capture of beads by the magnetic fields near the sensor. It is shown that beads can be washed off the sensor surface.

AB - Planar Hall effect magnetic sensors for detection of biological agents using surface treated magnetic beads are integrated with a fluid injection system. The response of the sensors is used to evaluate bead capture rates for different bead concentrations c and fluid flow rates Q, and to monitor subsequent removal of the beads. It is found that the capture rate scales directly with c and that it depends linearly on Q. At low Q the capture rate is only partially due to gravitational sedimentation of beads. At higher Q an additional term proportional to Q becomes important, which is attributed to capture of beads by the magnetic fields near the sensor. It is shown that beads can be washed off the sensor surface.

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DO - 10.1109/ICSENS.2008.4716426

M3 - Poster

T2 - 2008 IEEE Sensors

Y2 - 26 October 2008 through 29 October 2008

ER -

Bead Capture and Release on a Magnetic Sensor in a Microfluidic System

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