Banking feces: a new frontier for public blood banks?

a new frontier for public blood banks?

Simon Mark Dahl Jørgensen*, Christian Lodberg Hvas, Jens Frederik Dahlerup, Susan Mikkelsen, Lars Ehlers, Lianna Hede Hammeken, Tine Rask Licht, Martin Iain Bahl, Christian Erikstrup

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other microbiota-related disorders. The provision of FMT in routine clinical practice requires an extensive infrastructure that is reliant on voluntary donors. Alongside an increasing demand for FMT, the logistic barriers of a large-scale donor-dependent operation and the difficulties among health authorities to regulate FMT limit the dissemination of sustainable FMT services. Blood centers are large organizations that handle a multitude of donor-dependent operations on a daily basis. Blood and feces share many of the same dependencies, and feces may present a new opportunity for the blood services to handle. In this paper, we describe how an FMT service may be established and embedded within the blood service infrastructure, and we explain the benefits of using blood donors as feces donors. We further explore the current indications of FMT, the challenges related to the lack of legislation, and the future perspectives for blood banks to meet a new and increasing demand.
Original languageEnglish
JournalTransfusion
Volume59
Issue number9
Pages (from-to)2776-2782
ISSN0041-1132
DOIs
Publication statusPublished - 2019

Cite this

Jørgensen, S. M. D., Hvas, C. L., Dahlerup, J. F., Mikkelsen, S., Ehlers, L., Hammeken, L. H., ... Erikstrup, C. (2019). Banking feces: a new frontier for public blood banks? a new frontier for public blood banks? Transfusion, 59(9), 2776-2782. https://doi.org/10.1111/trf.15422
Jørgensen, Simon Mark Dahl ; Hvas, Christian Lodberg ; Dahlerup, Jens Frederik ; Mikkelsen, Susan ; Ehlers, Lars ; Hammeken, Lianna Hede ; Licht, Tine Rask ; Bahl, Martin Iain ; Erikstrup, Christian. / Banking feces: a new frontier for public blood banks? a new frontier for public blood banks?. In: Transfusion. 2019 ; Vol. 59, No. 9. pp. 2776-2782.
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title = "Banking feces: a new frontier for public blood banks?: a new frontier for public blood banks?",
abstract = "Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other microbiota-related disorders. The provision of FMT in routine clinical practice requires an extensive infrastructure that is reliant on voluntary donors. Alongside an increasing demand for FMT, the logistic barriers of a large-scale donor-dependent operation and the difficulties among health authorities to regulate FMT limit the dissemination of sustainable FMT services. Blood centers are large organizations that handle a multitude of donor-dependent operations on a daily basis. Blood and feces share many of the same dependencies, and feces may present a new opportunity for the blood services to handle. In this paper, we describe how an FMT service may be established and embedded within the blood service infrastructure, and we explain the benefits of using blood donors as feces donors. We further explore the current indications of FMT, the challenges related to the lack of legislation, and the future perspectives for blood banks to meet a new and increasing demand.",
author = "J{\o}rgensen, {Simon Mark Dahl} and Hvas, {Christian Lodberg} and Dahlerup, {Jens Frederik} and Susan Mikkelsen and Lars Ehlers and Hammeken, {Lianna Hede} and Licht, {Tine Rask} and Bahl, {Martin Iain} and Christian Erikstrup",
year = "2019",
doi = "10.1111/trf.15422",
language = "English",
volume = "59",
pages = "2776--2782",
journal = "Transfusion",
issn = "0041-1132",
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Jørgensen, SMD, Hvas, CL, Dahlerup, JF, Mikkelsen, S, Ehlers, L, Hammeken, LH, Licht, TR, Bahl, MI & Erikstrup, C 2019, 'Banking feces: a new frontier for public blood banks? a new frontier for public blood banks?', Transfusion, vol. 59, no. 9, pp. 2776-2782. https://doi.org/10.1111/trf.15422

Banking feces: a new frontier for public blood banks? a new frontier for public blood banks? / Jørgensen, Simon Mark Dahl; Hvas, Christian Lodberg; Dahlerup, Jens Frederik; Mikkelsen, Susan; Ehlers, Lars; Hammeken, Lianna Hede; Licht, Tine Rask; Bahl, Martin Iain; Erikstrup, Christian.

In: Transfusion, Vol. 59, No. 9, 2019, p. 2776-2782.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Banking feces: a new frontier for public blood banks?

T2 - a new frontier for public blood banks?

AU - Jørgensen, Simon Mark Dahl

AU - Hvas, Christian Lodberg

AU - Dahlerup, Jens Frederik

AU - Mikkelsen, Susan

AU - Ehlers, Lars

AU - Hammeken, Lianna Hede

AU - Licht, Tine Rask

AU - Bahl, Martin Iain

AU - Erikstrup, Christian

PY - 2019

Y1 - 2019

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AB - Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other microbiota-related disorders. The provision of FMT in routine clinical practice requires an extensive infrastructure that is reliant on voluntary donors. Alongside an increasing demand for FMT, the logistic barriers of a large-scale donor-dependent operation and the difficulties among health authorities to regulate FMT limit the dissemination of sustainable FMT services. Blood centers are large organizations that handle a multitude of donor-dependent operations on a daily basis. Blood and feces share many of the same dependencies, and feces may present a new opportunity for the blood services to handle. In this paper, we describe how an FMT service may be established and embedded within the blood service infrastructure, and we explain the benefits of using blood donors as feces donors. We further explore the current indications of FMT, the challenges related to the lack of legislation, and the future perspectives for blood banks to meet a new and increasing demand.

U2 - 10.1111/trf.15422

DO - 10.1111/trf.15422

M3 - Journal article

VL - 59

SP - 2776

EP - 2782

JO - Transfusion

JF - Transfusion

SN - 0041-1132

IS - 9

ER -

Jørgensen SMD, Hvas CL, Dahlerup JF, Mikkelsen S, Ehlers L, Hammeken LH et al. Banking feces: a new frontier for public blood banks? a new frontier for public blood banks? Transfusion. 2019;59(9):2776-2782. https://doi.org/10.1111/trf.15422