Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds

Miia Kontturi*, Reijo Junni, Heli Simojoki, Erja Malinen, Eija Seuna, Kirstine Klitgaard Schou, Minna Kujala-Wirth, Timo Soveri, Sinikka Pelkonen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

134 Downloads (Pure)

Abstract

Background: Severe outbreaks of bovine interdigital phlegmon (IP) have occurred recently in several free stall dairy herds in Finland. We studied the aetiology of IP in such herds, and the association of bacterial species with the various stages of IP and herds of various morbidity of IP. Nineteen free stall dairy herds with IP outbreaks and three control herds were visited and bacteriological samples collected from cows suffering from IP (n = 106), other hoof diseases (n = 58), and control cows (n = 64). The herds were divided into high morbidity (morbidity ≥50%) and moderate morbidity groups (9-33%) based on morbidity during the first two months of the outbreak. Results: F. necrophorum subspecies necrophorum was clearly associated with IP in general, and T. pyogenes was associated with the healing stage of IP. Six other major hoof pathogens were detected; Dichelobacter nodosus, Porphyromonas levii, Prevotella melaninogenica, Treponema spp. and Trueperella pyogenes. Most of the samples of acute IP (66.7%) harboured both F. necrophorum and D. nodosus. We found differences between moderate morbidity and high morbidity herds. D. nodosus was more common in IP lesion in high than in moderate morbidity herds. Conclusions: Our result confirms that F. necrophorum subspecies necrophorum is the main pathogen in IP, but also T. pyogenes is associated with the healing stage of IP. Our results suggest that D. nodosus may play a role in the severity of the outbreak of IP, but further research is needed to establish other bacteriological factors behind these severe outbreaks.

Original languageEnglish
Article number44
JournalBMC Veterinary Research
Volume15
Issue number1
Number of pages12
ISSN1746-6148
DOIs
Publication statusPublished - 29 Jan 2019

Keywords

  • Dichelobacter nodosus
  • Foot rot
  • Foul-in-the-foot
  • Fusobacterium necrophorum
  • Infectious hoof diseases
  • Interdigital necrobacillosis
  • Interdigital phlegmon

Cite this

Kontturi, M., Junni, R., Simojoki, H., Malinen, E., Seuna, E., Klitgaard Schou, K., ... Pelkonen, S. (2019). Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds. BMC Veterinary Research, 15(1), [44]. https://doi.org/10.1186/s12917-019-1788-x
Kontturi, Miia ; Junni, Reijo ; Simojoki, Heli ; Malinen, Erja ; Seuna, Eija ; Klitgaard Schou, Kirstine ; Kujala-Wirth, Minna ; Soveri, Timo ; Pelkonen, Sinikka. / Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds. In: BMC Veterinary Research. 2019 ; Vol. 15, No. 1.
@article{e982181c2bcf4cceaef67d7be521904a,
title = "Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds",
abstract = "Background: Severe outbreaks of bovine interdigital phlegmon (IP) have occurred recently in several free stall dairy herds in Finland. We studied the aetiology of IP in such herds, and the association of bacterial species with the various stages of IP and herds of various morbidity of IP. Nineteen free stall dairy herds with IP outbreaks and three control herds were visited and bacteriological samples collected from cows suffering from IP (n = 106), other hoof diseases (n = 58), and control cows (n = 64). The herds were divided into high morbidity (morbidity ≥50{\%}) and moderate morbidity groups (9-33{\%}) based on morbidity during the first two months of the outbreak. Results: F. necrophorum subspecies necrophorum was clearly associated with IP in general, and T. pyogenes was associated with the healing stage of IP. Six other major hoof pathogens were detected; Dichelobacter nodosus, Porphyromonas levii, Prevotella melaninogenica, Treponema spp. and Trueperella pyogenes. Most of the samples of acute IP (66.7{\%}) harboured both F. necrophorum and D. nodosus. We found differences between moderate morbidity and high morbidity herds. D. nodosus was more common in IP lesion in high than in moderate morbidity herds. Conclusions: Our result confirms that F. necrophorum subspecies necrophorum is the main pathogen in IP, but also T. pyogenes is associated with the healing stage of IP. Our results suggest that D. nodosus may play a role in the severity of the outbreak of IP, but further research is needed to establish other bacteriological factors behind these severe outbreaks.",
keywords = "Dichelobacter nodosus, Foot rot, Foul-in-the-foot, Fusobacterium necrophorum, Infectious hoof diseases, Interdigital necrobacillosis, Interdigital phlegmon",
author = "Miia Kontturi and Reijo Junni and Heli Simojoki and Erja Malinen and Eija Seuna and {Klitgaard Schou}, Kirstine and Minna Kujala-Wirth and Timo Soveri and Sinikka Pelkonen",
year = "2019",
month = "1",
day = "29",
doi = "10.1186/s12917-019-1788-x",
language = "English",
volume = "15",
journal = "B M C Veterinary Research",
issn = "1746-6148",
publisher = "BioMed Central Ltd.",
number = "1",

}

Kontturi, M, Junni, R, Simojoki, H, Malinen, E, Seuna, E, Klitgaard Schou, K, Kujala-Wirth, M, Soveri, T & Pelkonen, S 2019, 'Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds', BMC Veterinary Research, vol. 15, no. 1, 44. https://doi.org/10.1186/s12917-019-1788-x

Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds. / Kontturi, Miia; Junni, Reijo; Simojoki, Heli; Malinen, Erja; Seuna, Eija; Klitgaard Schou, Kirstine; Kujala-Wirth, Minna; Soveri, Timo; Pelkonen, Sinikka.

In: BMC Veterinary Research, Vol. 15, No. 1, 44, 29.01.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds

AU - Kontturi, Miia

AU - Junni, Reijo

AU - Simojoki, Heli

AU - Malinen, Erja

AU - Seuna, Eija

AU - Klitgaard Schou, Kirstine

AU - Kujala-Wirth, Minna

AU - Soveri, Timo

AU - Pelkonen, Sinikka

PY - 2019/1/29

Y1 - 2019/1/29

N2 - Background: Severe outbreaks of bovine interdigital phlegmon (IP) have occurred recently in several free stall dairy herds in Finland. We studied the aetiology of IP in such herds, and the association of bacterial species with the various stages of IP and herds of various morbidity of IP. Nineteen free stall dairy herds with IP outbreaks and three control herds were visited and bacteriological samples collected from cows suffering from IP (n = 106), other hoof diseases (n = 58), and control cows (n = 64). The herds were divided into high morbidity (morbidity ≥50%) and moderate morbidity groups (9-33%) based on morbidity during the first two months of the outbreak. Results: F. necrophorum subspecies necrophorum was clearly associated with IP in general, and T. pyogenes was associated with the healing stage of IP. Six other major hoof pathogens were detected; Dichelobacter nodosus, Porphyromonas levii, Prevotella melaninogenica, Treponema spp. and Trueperella pyogenes. Most of the samples of acute IP (66.7%) harboured both F. necrophorum and D. nodosus. We found differences between moderate morbidity and high morbidity herds. D. nodosus was more common in IP lesion in high than in moderate morbidity herds. Conclusions: Our result confirms that F. necrophorum subspecies necrophorum is the main pathogen in IP, but also T. pyogenes is associated with the healing stage of IP. Our results suggest that D. nodosus may play a role in the severity of the outbreak of IP, but further research is needed to establish other bacteriological factors behind these severe outbreaks.

AB - Background: Severe outbreaks of bovine interdigital phlegmon (IP) have occurred recently in several free stall dairy herds in Finland. We studied the aetiology of IP in such herds, and the association of bacterial species with the various stages of IP and herds of various morbidity of IP. Nineteen free stall dairy herds with IP outbreaks and three control herds were visited and bacteriological samples collected from cows suffering from IP (n = 106), other hoof diseases (n = 58), and control cows (n = 64). The herds were divided into high morbidity (morbidity ≥50%) and moderate morbidity groups (9-33%) based on morbidity during the first two months of the outbreak. Results: F. necrophorum subspecies necrophorum was clearly associated with IP in general, and T. pyogenes was associated with the healing stage of IP. Six other major hoof pathogens were detected; Dichelobacter nodosus, Porphyromonas levii, Prevotella melaninogenica, Treponema spp. and Trueperella pyogenes. Most of the samples of acute IP (66.7%) harboured both F. necrophorum and D. nodosus. We found differences between moderate morbidity and high morbidity herds. D. nodosus was more common in IP lesion in high than in moderate morbidity herds. Conclusions: Our result confirms that F. necrophorum subspecies necrophorum is the main pathogen in IP, but also T. pyogenes is associated with the healing stage of IP. Our results suggest that D. nodosus may play a role in the severity of the outbreak of IP, but further research is needed to establish other bacteriological factors behind these severe outbreaks.

KW - Dichelobacter nodosus

KW - Foot rot

KW - Foul-in-the-foot

KW - Fusobacterium necrophorum

KW - Infectious hoof diseases

KW - Interdigital necrobacillosis

KW - Interdigital phlegmon

U2 - 10.1186/s12917-019-1788-x

DO - 10.1186/s12917-019-1788-x

M3 - Journal article

VL - 15

JO - B M C Veterinary Research

JF - B M C Veterinary Research

SN - 1746-6148

IS - 1

M1 - 44

ER -

Kontturi M, Junni R, Simojoki H, Malinen E, Seuna E, Klitgaard Schou K et al. Bacterial species associated with interdigital phlegmon outbreaks in Finnish dairy herds. BMC Veterinary Research. 2019 Jan 29;15(1). 44. https://doi.org/10.1186/s12917-019-1788-x