Automated quantification and analysis of mandibular asymmetry

T. A. Darvann; N. V. Hermann; P. Larsen; Hildur Ólafsdóttir; I. V. Hansen; H. D. Hove; L. Christensen; D. Rueckert; S. Kreiborg

doi:10.1109/ISBI.2010.5490320

Automated quantification and analysis of mandibular asymmetry

T. A. Darvann, N. V. Hermann, P. Larsen, Hildur Ólafsdóttir, I. V. Hansen, H. D. Hove, L. Christensen, D. Rueckert, S. Kreiborg

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Abstract

We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.

Original language	English
Title of host publication	2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro
Publisher	IEEE
Publication date	2010
Pages	416-419
ISBN (Print)	978-1-4244-4125-9
DOIs	https://doi.org/10.1109/ISBI.2010.5490320
Publication status	Published - 2010
Event	2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Rotterdam, Netherlands Duration: 14 Apr 2010 → 17 Apr 2010 Conference number: 7 http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=5481762

Conference

Conference	2010 IEEE International Symposium on Biomedical Imaging
Number	7
Country/Territory	Netherlands
City	Rotterdam
Period	14/04/2010 → 17/04/2010
Internet address	http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=5481762

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Copyright 2010 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.

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@inproceedings{f05303c03b9340b793ac58ec7147038d,

title = "Automated quantification and analysis of mandibular asymmetry",

abstract = "We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.",

author = "Darvann, {T. A.} and Hermann, {N. V.} and P. Larsen and Hildur {\'O}lafsd{\'o}ttir and Hansen, {I. V.} and Hove, {H. D.} and L. Christensen and D. Rueckert and S. Kreiborg",

note = "Copyright 2010 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.; 2010 IEEE International Symposium on Biomedical Imaging : From Nano to Macro, ISBI 2010 ; Conference date: 14-04-2010 Through 17-04-2010",

year = "2010",

doi = "10.1109/ISBI.2010.5490320",

language = "English",

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booktitle = "2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro",

publisher = "IEEE",

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Darvann, TA, Hermann, NV, Larsen, P, Ólafsdóttir, H, Hansen, IV, Hove, HD, Christensen, L, Rueckert, D & Kreiborg, S 2010, Automated quantification and analysis of mandibular asymmetry. in 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro. IEEE, pp. 416-419, 2010 IEEE International Symposium on Biomedical Imaging, Rotterdam, Netherlands, 14/04/2010. https://doi.org/10.1109/ISBI.2010.5490320

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T1 - Automated quantification and analysis of mandibular asymmetry

AU - Darvann, T. A.

AU - Hermann, N. V.

AU - Larsen, P.

AU - Ólafsdóttir, Hildur

AU - Hansen, I. V.

AU - Hove, H. D.

AU - Christensen, L.

AU - Rueckert, D.

AU - Kreiborg, S.

N1 - Conference code: 7

PY - 2010

Y1 - 2010

N2 - We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.

AB - We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.

U2 - 10.1109/ISBI.2010.5490320

DO - 10.1109/ISBI.2010.5490320

M3 - Article in proceedings

SN - 978-1-4244-4125-9

SP - 416

EP - 419

BT - 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro

PB - IEEE

T2 - 2010 IEEE International Symposium on Biomedical Imaging

Y2 - 14 April 2010 through 17 April 2010

ER -

Automated quantification and analysis of mandibular asymmetry

Abstract

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