Abstract
A quantitative analysis of metastatic bone involvement can be an important prognostic indicator of survival or a tool in monitoring treatment response in patients with cancer. The purpose of this study was to develop a completely automated decision support system for whole-body bone scans using image analysis and artificial neural networks. The study population consisted of 795 whole-body bone scans. The decision support system first detects and classifies individual hotspots as being metastatic or not. A second prediction model then classifies the scan regarding metastatic disease on a patient level. The test set sensitivity and specificity was 95% and 64% respectively, corresponding to 95% area under the receiver operating characteristics curve. ©2009 IEEE.
| Original language | English |
|---|---|
| Title of host publication | Proceedings - IEEE Symposium on Computer-Based Medical Systems |
| Number of pages | 5255270 |
| Publisher | IEEE |
| Publication date | 2009 |
| ISBN (Print) | 9781424448784 |
| DOIs | |
| Publication status | Published - 2009 |
| Externally published | Yes |
| Event | 2009 22nd IEEE International Symposium on Computer-Based Medical Systems - Albuquerque, United States Duration: 2 Aug 2009 → 5 Aug 2009 Conference number: 22 https://ieeexplore.ieee.org/xpl/conhome/5230478/proceeding |
Conference
| Conference | 2009 22nd IEEE International Symposium on Computer-Based Medical Systems |
|---|---|
| Number | 22 |
| Country/Territory | United States |
| City | Albuquerque |
| Period | 02/08/2009 → 05/08/2009 |
| Internet address |