TY - JOUR
T1 - Audouin's gull, a potential vehicle of an extended spectrum beta-lactamase producing Salmonella Agona
AU - Antilles, Noelia
AU - Garcia-Migura, Lourdes
AU - Joensen, Katrine Grimstrup
AU - Leekitcharoenphon, Pimlapas
AU - Aarestrup, Frank Møller
AU - Cerda-Cuellar, Marta
AU - Hendriksen, Rene S.
PY - 2015
Y1 - 2015
N2 - The genome of a multidrug-resistant Salmonella Agona isolated from Larus audouinii (Audouin's gull) in Spain was examined. The isolate showed high levels of resistance to different antimicrobials, including third generation cephalosporins and fluoroquinolones, which is a public health concern as those being used to treat severe salmonellosis in humans. Whole genome sequencing revealed the strain being multilocus sequence type ST13, and eight resistance genes (aadA2, aadB, bla(CTX-M-9), bla(DHA-1), qnrA1, tetA, sul1 and dfrA16) belonging to seven antimicrobial classes were confirmed, as well as the presence of two plasmids. Migratory Audouin's gulls have the ability to cover long distances during annual movements. Therefore, they have the potential to disseminate multidrug-resistant Salmonella and resistance genes in the environment and over great geographic distances, contributing to the global dissemination of resistance genes.
AB - The genome of a multidrug-resistant Salmonella Agona isolated from Larus audouinii (Audouin's gull) in Spain was examined. The isolate showed high levels of resistance to different antimicrobials, including third generation cephalosporins and fluoroquinolones, which is a public health concern as those being used to treat severe salmonellosis in humans. Whole genome sequencing revealed the strain being multilocus sequence type ST13, and eight resistance genes (aadA2, aadB, bla(CTX-M-9), bla(DHA-1), qnrA1, tetA, sul1 and dfrA16) belonging to seven antimicrobial classes were confirmed, as well as the presence of two plasmids. Migratory Audouin's gulls have the ability to cover long distances during annual movements. Therefore, they have the potential to disseminate multidrug-resistant Salmonella and resistance genes in the environment and over great geographic distances, contributing to the global dissemination of resistance genes.
U2 - 10.1093/femsle/fnu039
DO - 10.1093/femsle/fnu039
M3 - Journal article
C2 - 25673651
SN - 0378-1097
VL - 362
SP - 1
EP - 4
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
IS - 3
ER -
