Attenuated Heart Rate Response is Associated with Hypocretin Deficiency in Patients with Narcolepsy.

Gertrud Laura Sørensen; Stine Knudsen; Eva Rosa Petersen; Jacob Kempfner; Steen Gammeltoft; Helge Bjarup Dissing Sørensen; Poul Jennum

doi:10.5665/sleep.2308

Attenuated Heart Rate Response is Associated with Hypocretin Deficiency in Patients with Narcolepsy.

Gertrud Laura Sørensen, Stine Knudsen, Eva Rosa Petersen, Jacob Kempfner, Steen Gammeltoft, Helge Bjarup Dissing Sørensen, Poul Jennum

Copenhagen University Hospital Herlev and Gentofte

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Our results show that autonomic dysfunction is part of the narcoleptic phenotype, and that hypocretin-1 deficiency is the primary predictor of this dysfunction. This finding suggests that the hypocretin system participates in the modulation of cardiovascular function at rest. CITATION: Sorensen GL; Knudsen S; Petersen ER; Kempfner J; Gammeltoft S; Sorensen HBD; Jennum P. Attenuated heart rate response is associated with hypocretin deficiency in patients with narcolepsy. SLEEP 2013;36(1):91-98.

Original language	English
Journal	Sleep
Volume	36
Issue number	1
Pages (from-to)	91-98
ISSN	0161-8105
DOIs	https://doi.org/10.5665/sleep.2308
Publication status	Published - 2013

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title = "Attenuated Heart Rate Response is Associated with Hypocretin Deficiency in Patients with Narcolepsy.",

abstract = "Our results show that autonomic dysfunction is part of the narcoleptic phenotype, and that hypocretin-1 deficiency is the primary predictor of this dysfunction. This finding suggests that the hypocretin system participates in the modulation of cardiovascular function at rest. CITATION: Sorensen GL; Knudsen S; Petersen ER; Kempfner J; Gammeltoft S; Sorensen HBD; Jennum P. Attenuated heart rate response is associated with hypocretin deficiency in patients with narcolepsy. SLEEP 2013;36(1):91-98.",

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year = "2013",

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AU - Sørensen, Gertrud Laura

AU - Knudsen, Stine

AU - Petersen, Eva Rosa

AU - Kempfner, Jacob

AU - Gammeltoft, Steen

AU - Sørensen, Helge Bjarup Dissing

AU - Jennum, Poul

PY - 2013

Y1 - 2013

N2 - Our results show that autonomic dysfunction is part of the narcoleptic phenotype, and that hypocretin-1 deficiency is the primary predictor of this dysfunction. This finding suggests that the hypocretin system participates in the modulation of cardiovascular function at rest. CITATION: Sorensen GL; Knudsen S; Petersen ER; Kempfner J; Gammeltoft S; Sorensen HBD; Jennum P. Attenuated heart rate response is associated with hypocretin deficiency in patients with narcolepsy. SLEEP 2013;36(1):91-98.

AB - Our results show that autonomic dysfunction is part of the narcoleptic phenotype, and that hypocretin-1 deficiency is the primary predictor of this dysfunction. This finding suggests that the hypocretin system participates in the modulation of cardiovascular function at rest. CITATION: Sorensen GL; Knudsen S; Petersen ER; Kempfner J; Gammeltoft S; Sorensen HBD; Jennum P. Attenuated heart rate response is associated with hypocretin deficiency in patients with narcolepsy. SLEEP 2013;36(1):91-98.

U2 - 10.5665/sleep.2308

DO - 10.5665/sleep.2308

M3 - Journal article

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JO - Sleep

JF - Sleep

IS - 1

ER -

Attenuated Heart Rate Response is Associated with Hypocretin Deficiency in Patients with Narcolepsy.

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