Attenuated Heart Rate Response is Associated with Hypocretin Deficiency in Patients with Narcolepsy.

Gertrud Laura Sørensen, Stine Knudsen, Eva Rosa Petersen, Jacob Kempfner, Steen Gammeltoft, Helge Bjarup Dissing Sørensen, Poul Jennum

Research output: Contribution to journalJournal articleResearchpeer-review


Our results show that autonomic dysfunction is part of the narcoleptic phenotype, and that hypocretin-1 deficiency is the primary predictor of this dysfunction. This finding suggests that the hypocretin system participates in the modulation of cardiovascular function at rest. CITATION: Sorensen GL; Knudsen S; Petersen ER; Kempfner J; Gammeltoft S; Sorensen HBD; Jennum P. Attenuated heart rate response is associated with hypocretin deficiency in patients with narcolepsy. SLEEP 2013;36(1):91-98.
Original languageEnglish
Issue number1
Pages (from-to)91-98
Publication statusPublished - 2013

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