Asymmetric Horner-Wadsworth-Emmons Reactions with                meso-Dialdehydes: Scope, Mechanism, and Synthetic Applications

Tobias Rein; Lauri Vares; Ikuo Kawasaki; Torben M. Pedersen; Per-Ola Norrby; Peter Brandt; David Ackland Tanner

Asymmetric Horner-Wadsworth-Emmons Reactions with meso-Dialdehydes: Scope, Mechanism, and Synthetic Applications

Tobias Rein
, Lauri Vares
, Ikuo Kawasaki
, Torben M. Pedersen
, Per-Ola Norrby
, Peter Brandt
, David Ackland Tanner

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Asymmetric Homer-Wadsworth-Emmons reactions between chiral phosphonate reagents and various meso-dialdehydes have been investigated. A mechanistic model useful for rationalizing the experimentally observed stereoselectivities is presented. Furthermore; strategies for applying these reactions to the stereocontrolled preparation of chiral heterocyclic building blocks have been developed.

Original language	English
Journal	Phosphorus, Sulfur and Silicon and the Related Elements
Volume	144-146
Pages (from-to)	169-172
ISSN	1042-6507
Publication status	Published - 1999
Event	XIV International Conference on Phosphorus Chemistry - Cincinnati,OH, United States Duration: 12 Jul 1998 → 17 Jul 1998 Conference number: 14

Conference

Conference	XIV International Conference on Phosphorus Chemistry
Number	14
Country/Territory	United States
City	Cincinnati,OH
Period	12/07/1998 → 17/07/1998

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title = "Asymmetric Horner-Wadsworth-Emmons Reactions with meso-Dialdehydes: Scope, Mechanism, and Synthetic Applications",

abstract = "Asymmetric Homer-Wadsworth-Emmons reactions between chiral phosphonate reagents and various meso-dialdehydes have been investigated. A mechanistic model useful for rationalizing the experimentally observed stereoselectivities is presented. Furthermore; strategies for applying these reactions to the stereocontrolled preparation of chiral heterocyclic building blocks have been developed. ",

author = "Tobias Rein and Lauri Vares and Ikuo Kawasaki and Pedersen, \{Torben M.\} and Per-Ola Norrby and Peter Brandt and Tanner, \{David Ackland\}",

year = "1999",

language = "English",

volume = "144-146",

pages = "169--172",

journal = "Phosphorus, Sulfur and Silicon and the Related Elements",

issn = "1042-6507",

publisher = "Taylor and Francis Ltd.",

note = "XIV International Conference on Phosphorus Chemistry ; Conference date: 12-07-1998 Through 17-07-1998",

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TY - JOUR

T1 - Asymmetric Horner-Wadsworth-Emmons Reactions with meso-Dialdehydes: Scope, Mechanism, and Synthetic Applications

AU - Rein, Tobias

AU - Vares, Lauri

AU - Kawasaki, Ikuo

AU - Pedersen, Torben M.

AU - Norrby, Per-Ola

AU - Brandt, Peter

AU - Tanner, David Ackland

N1 - Conference code: 14

PY - 1999

Y1 - 1999

N2 - Asymmetric Homer-Wadsworth-Emmons reactions between chiral phosphonate reagents and various meso-dialdehydes have been investigated. A mechanistic model useful for rationalizing the experimentally observed stereoselectivities is presented. Furthermore; strategies for applying these reactions to the stereocontrolled preparation of chiral heterocyclic building blocks have been developed.

AB - Asymmetric Homer-Wadsworth-Emmons reactions between chiral phosphonate reagents and various meso-dialdehydes have been investigated. A mechanistic model useful for rationalizing the experimentally observed stereoselectivities is presented. Furthermore; strategies for applying these reactions to the stereocontrolled preparation of chiral heterocyclic building blocks have been developed.

M3 - Journal article

SN - 1042-6507

VL - 144-146

SP - 169

EP - 172

JO - Phosphorus, Sulfur and Silicon and the Related Elements

JF - Phosphorus, Sulfur and Silicon and the Related Elements

T2 - XIV International Conference on Phosphorus Chemistry

Y2 - 12 July 1998 through 17 July 1998

ER -

Asymmetric Horner-Wadsworth-Emmons Reactions with meso-Dialdehydes: Scope, Mechanism, and Synthetic Applications

Abstract

Conference

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