Associations of Neospora caninum seropositivity with gestation number and pregnancy outcome in Danish dairy herds

Anette Møllegaard Jensen, C. Bjorkman, A.M. Kjeldsen, A. Wedderkopp, C. Willadsen, A. Uggla, Peter Lind

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    The prevalence and distribution of seropositivity towards the protozoan parasite Neospora caninum were studied in single blood samples from 1561 cows from 31 Danish dairy herds. Blood samples were analysed by an indirect enzyme-linked immunoassay and an indirect fluorescent-antibody test, Seroprevalence in 15 herds with previous abortions assigned to neosporosis ranged from I% to 58%, with a mean frequency of 22%. In eight out of 16 herds without a history of N. caninum related abortions, no seroreactors were found. In the remaining eight herds, the seroprevalence ranged from 6% to 59%. The prevalence and distribution of seropositivity, gestation number prior to sampling, and breed were related to abortions and perinatal deaths using a random-effects logistic-regression model. Abortion risk was significantly increased in seropositive animals (OR=3) and in greater than or equal to 2nd-gestation cows (OR=3). Perinatal death was significantly influenced by gestation number and breed, but not by serostatus, Reproductive performance and culling risk of cows were not affected by serostatus. Seropositivity increased with "age" (i.e, gestation number) (P=0.02). In open cows, seropositivity tended to decrease with distance from calving (P=0.05). The proportion of seropositive pregnant cows increased with trimester (P=0.02).
    Original languageEnglish
    JournalPreventive Veterinary Medicine
    Volume40
    Issue number3-4
    Pages (from-to)151-163
    ISSN0167-5877
    Publication statusPublished - 1999

    Keywords

    • Neospora caninum
    • parasitological disease
    • abortion
    • serology
    • cattle

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