Assessing the Accuracy of Prediction Algorithms for Classification: An Overview

P. Baldi, Søren Brunak, Y. Chauvin, Henrik Nielsen

    Research output: Contribution to journalJournal articleResearchpeer-review


    We provide a unified overview of methods that currently are widely used to assess the accuracy of prediction algorithms, from raw percentages, quadratic error measures and other distances, ann correlation coefficients, and to information theoretic measures such as relative entropy and mutual information. We briefly discuss the advantages and disadvantages of each approach. For classification tasks, we derive new learning algorithms for the design of prediction systems by directly optimising the correlation coefficient. We observe and prove several results relating sensitivity nod specificity of optimal systems. While the principles are general, we illustrate the applicability on specific problems such as protein secondary structure and signal peptide prediction.
    Original languageEnglish
    Issue number5
    Pages (from-to)412-424
    Publication statusPublished - 2000


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