ASL: Comparison of presaturation and RF pulse optimization

David Holm, Karam Sidaros

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    Abstract

    In arterial spin labelling, the difference between the tag and control image is on the order of 1% of the equilibrium magnetization. A small offset between the images not related to perfusion, can therefore lead to large errors in the measured perfusion. One source of error is non-ideal RF pulses resulting in the inversion pulse affecting the acquired signal from the imaging area. This systematic error can be reduced by increasing the gap between the inversion and imaging regions, by using optimized inversion pulses e.g. FOCI1 or by saturating the signal from static tissue in the imaging area prior to acquiring the image. In this simulation study, the use of presaturation is compared with using optimized RF pulses. Furthermore the effect of using and optimizing crusher gradients is reported.
    Original languageEnglish
    Title of host publicationProc. International Society of Magnetic Resonance In Medicine - ISMRM 2005, Miami, Florida, USA
    Number of pages1153
    Publication date2005
    Publication statusPublished - 2005
    Event13th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance In Medicine - Miami, FL, United States
    Duration: 7 May 200513 May 2005

    Conference

    Conference13th Scientific Meeting & Exhibition of the International Society of Magnetic Resonance In Medicine
    CountryUnited States
    CityMiami, FL
    Period07/05/200513/05/2005

    Cite this

    Holm, D., & Sidaros, K. (2005). ASL: Comparison of presaturation and RF pulse optimization. In Proc. International Society of Magnetic Resonance In Medicine - ISMRM 2005, Miami, Florida, USA http://www2.imm.dtu.dk/pubdb/p.php?3595