Arylalkylamine n-acetyltransferase and uses thereof

Hao Luo (Inventor)

Research output: Patent

127 Downloads (Pure)


Described herein are variants of arylalkylamine N-acetyltransferase (AANAT) as well as vectors and recombinant microbial host cells expressing AANATs and variant AANATs and their use in producing N-acetylserotonin, melatonin and related compounds. Preferred AANAT variants provide for an increased yield of N-acetylserotonin.
Original languageEnglish
IPCC12N9/10; C12N15/00; C12N5/00
Patent numberWO2018108966
Filing date21/06/2018
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date13/12/2016
Priority numberEP20160203711
Publication statusPublished - 2018


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