Application of Functional Nano-Patterning to Polymer Medical Micro Implants

Giuliano Bissacco, Francesco Giuseppe Biondani, P.T. Tang, Michael Mischkot, Hans Nørgaard Hansen, Yang Zhang, Christian Ravn

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

Improvement of cells adhesion to medical implants can be achieved through specific surface nano-patterns. The application of nano-patterns to planar surfaces can be obtained in a number of ways. However, the application of functional nano-patterns to complex 3D surfaces is a challenging task. In this paper the application of a nano-pattern deriving from aluminium anodizing to 3D micro mould inserts for replication of polymer medical micro implants is described. A process chain earlier developed at DTU was applied, where the main steps include the fabrication of an aluminium master, anodizing, etching of aluminium oxide, nickel and copper electroplating and selective etching of the aluminium master. The resulting nanostructure consists of tightly packed hemispherical features with average diameter of approximately 400 nm. Characterization of the obtained nanostructure on the micro mould inserts was carried out by means of atomic force microscopy and scanning electron microscopy. Results show that the specific nano-pattern was successfully generated on the 3D mould inserts exploiting the proposed process chain.
Original languageEnglish
Title of host publicationProceedings of the 4M/ICOMM2015 Conference
EditorsMassimiliano Annoni, Irene Fassi, Gloria J. Wiens, Stefan Dimov
Number of pages4
PublisherResearch Publishing Services
Publication date2015
ISBN (Electronic)978-981-09-4609-8
DOIs
Publication statusPublished - 2015
Event4M/ICOMM2015 Conference - Milan, Italy
Duration: 31 Mar 20152 Apr 2015
http://www.4m-association.org/conference/2015

Conference

Conference4M/ICOMM2015 Conference
CountryItaly
CityMilan
Period31/03/201502/04/2015
Internet address

Keywords

  • Nano pattern
  • Medical devices
  • Process chains

Cite this

Bissacco, G., Biondani, F. G., Tang, P. T., Mischkot, M., Hansen, H. N., Zhang, Y., & Ravn, C. (2015). Application of Functional Nano-Patterning to Polymer Medical Micro Implants. In M. Annoni, I. Fassi, G. J. Wiens, & S. Dimov (Eds.), Proceedings of the 4M/ICOMM2015 Conference Research Publishing Services. https://doi.org/10.3850/978-981-09-4609-8_118