Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs

Research output: Contribution to journalConference abstract in journal – Annual report year: 2018Researchpeer-review

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Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs. / Shim, J.; Poulsen, C. B.; Hagensen, M.; Larsen, T.; Heegaard, P. M. H.; Christoffersen, C.; Bolund, L.; Schmidt, M.; Liu, Y.; Li, J.; Li, R.; Callesen, H.; Bentzon, J. F.; Sørensen, C. B.

In: Transgenic Research, Vol. 27, No. 5, 2018, p. 484-484.

Research output: Contribution to journalConference abstract in journal – Annual report year: 2018Researchpeer-review

Harvard

Shim, J, Poulsen, CB, Hagensen, M, Larsen, T, Heegaard, PMH, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, JF & Sørensen, CB 2018, 'Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs', Transgenic Research, vol. 27, no. 5, pp. 484-484. https://doi.org/10.1007/s11248-018-0086-x

APA

CBE

Shim J, Poulsen CB, Hagensen M, Larsen T, Heegaard PMH, Christoffersen C, Bolund L, Schmidt M, Liu Y, Li J, Li R, Callesen H, Bentzon JF, Sørensen CB. 2018. Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs. Transgenic Research. 27(5):484-484. https://doi.org/10.1007/s11248-018-0086-x

MLA

Vancouver

Author

Shim, J. ; Poulsen, C. B. ; Hagensen, M. ; Larsen, T. ; Heegaard, P. M. H. ; Christoffersen, C. ; Bolund, L. ; Schmidt, M. ; Liu, Y. ; Li, J. ; Li, R. ; Callesen, H. ; Bentzon, J. F. ; Sørensen, C. B. / Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs. In: Transgenic Research. 2018 ; Vol. 27, No. 5. pp. 484-484.

Bibtex

@article{5dd5f24e9eaf4270be0a5e58b2b64849,
title = "Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs",
abstract = "Apolipoprotein E (APOE) mediates hepatic uptake of lipoproteins through the low-density lipoprotein receptor and low-density receptor-related protein 1. Defects or deficiency of APOE causes familial dysbetalipoproteinemia in humans characterized by accumulations of VLDL, IDL, and chylomicron remnants as well as a higher risk of atherosclerotic disease. APOE is also involved in controlling smooth muscle cell proliferation and migration, reverse cholesterol transport and inflammation.",
author = "J. Shim and Poulsen, {C. B.} and M. Hagensen and T. Larsen and Heegaard, {P. M. H.} and C. Christoffersen and L. Bolund and M. Schmidt and Y. Liu and J. Li and R. Li and H. Callesen and Bentzon, {J. F.} and S{\o}rensen, {C. B.}",
year = "2018",
doi = "10.1007/s11248-018-0086-x",
language = "English",
volume = "27",
pages = "484--484",
journal = "Transgenic Research",
issn = "0962-8819",
publisher = "Springer Netherlands",
number = "5",

}

RIS

TY - ABST

T1 - Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs

AU - Shim, J.

AU - Poulsen, C. B.

AU - Hagensen, M.

AU - Larsen, T.

AU - Heegaard, P. M. H.

AU - Christoffersen, C.

AU - Bolund, L.

AU - Schmidt, M.

AU - Liu, Y.

AU - Li, J.

AU - Li, R.

AU - Callesen, H.

AU - Bentzon, J. F.

AU - Sørensen, C. B.

PY - 2018

Y1 - 2018

N2 - Apolipoprotein E (APOE) mediates hepatic uptake of lipoproteins through the low-density lipoprotein receptor and low-density receptor-related protein 1. Defects or deficiency of APOE causes familial dysbetalipoproteinemia in humans characterized by accumulations of VLDL, IDL, and chylomicron remnants as well as a higher risk of atherosclerotic disease. APOE is also involved in controlling smooth muscle cell proliferation and migration, reverse cholesterol transport and inflammation.

AB - Apolipoprotein E (APOE) mediates hepatic uptake of lipoproteins through the low-density lipoprotein receptor and low-density receptor-related protein 1. Defects or deficiency of APOE causes familial dysbetalipoproteinemia in humans characterized by accumulations of VLDL, IDL, and chylomicron remnants as well as a higher risk of atherosclerotic disease. APOE is also involved in controlling smooth muscle cell proliferation and migration, reverse cholesterol transport and inflammation.

U2 - 10.1007/s11248-018-0086-x

DO - 10.1007/s11248-018-0086-x

M3 - Conference abstract in journal

VL - 27

SP - 484

EP - 484

JO - Transgenic Research

JF - Transgenic Research

SN - 0962-8819

IS - 5

ER -