Antioxidant Efficacies of Rutin and Rutin Esters in Bulk Oil and Oil-in-Water Emulsion

Bena-Marie Lue, Ann-Dorit Moltke Sørensen, Charlotte Jacobsen, Zheng Guo, Xuebing Xu

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The use of flavonoids as antioxidants in food formulations is limited due to their solubility and thereby their localization in the food products. However, enzymatic alkylation of flavonoids with lipophilic moieties alters their lipophilicity and thereby partitioning within different phases in a food product. This study aimed to evaluate the antioxidative efficiency of two derivatives of rutin, namely rutin laurate (C12:0) and rutin palmitate (C16:0) compared with their parent compound rutin and with butylated hydroxytoluene (BHT). Their efficiency as antioxidants at two different concentrations (25 and 200 µM) was assessed in bulk oil and in an o/w emulsion system without and with iron addition. All evaluated compounds revealed antioxidant effects. However, rutin and BHT were the most efficient antioxidants in bulk oil followed by rutin palmitate, whereas rutin laurate acted as either an antioxidant or a prooxidant at low and high concentrations (25 and 200 µM), respectively. In emulsions, rutin and BHT in high concentration (200 µM) were more efficient than rutin esters. Thus, alcylation of rutin with medium chain fatty acids did not improve the antioxidant ability, neither in bulk oil nor in o/w emulsion. Interestingly, rutin had stronger antioxidative effect than BHT upon iron addition to the emulsion.

Practical application: According to the antioxidant hypothesis the polar paradox more amphiphilic antioxidants should perform as better antioxidants in emulsions than more polar antioxidants. The finding in this study revealed that lipophilization of rutin did not improve its antioxidant capacity in emulsions compared to untreated rutin. This stresses the importance of evaluating the antioxidant in each emulsion systems before selecting appropriate antioxidants for optimal protection against lipid oxidation.
Original languageEnglish
Article number1600049
JournalEuropean Journal of Lipid Science and Technology
Volume119
Issue number4
Number of pages15
ISSN1438-7697
DOIs
Publication statusPublished - 2017

Keywords

  • Lipid oxidation
  • Flavonoid esters
  • Partitioning
  • Rutin laurate
  • Rutin palmitate

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