Antibody titers against swine influenza subtypes determined by the hemagglutination inhibition test are highly dependent on the strain

Ramona Trebbien, Jens Nielsen, Anette Bøtner, Charlotte Kristiane Hjulsager, Lars Erik Larsen

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    Abstract

    In Denmark there are three circulating strains of swine influenza H1N1, H1N2 and H3N2. The H1N2 is different from the H1N2 subtypes circulating in other European countries. The Danish subtype is a reassortment between the two Danish circulating swine influenza subtypes H1N1 and H3N2. From a diagnostic and epidemiological point of view it is crucial to clarify whether the immunological response to one subtype protects against infection with the other subtype. The hemagglutination inhibition test (HI-test) has been used widely to determine the presence of antibodies in serum against influenza viruses. In the present study the HI-test was used to determine antibody response from experimental infected pigs. The aim of the study was to evaluate the antibody response against the new Danish influenza subtype H1N2 (H1N2dk) and to examine the level of crossprotection/reaction between the two influenza subtypes.
    Original languageEnglish
    Publication date2008
    Publication statusPublished - 2008
    Event20th International Pig Veterinary Society Congress - Durban, South Africa
    Duration: 22 Jun 200826 Jun 2008

    Conference

    Conference20th International Pig Veterinary Society Congress
    CountrySouth Africa
    CityDurban
    Period22/06/200826/06/2008

    Cite this

    Trebbien, R., Nielsen, J., Bøtner, A., Hjulsager, C. K., & Larsen, L. E. (2008). Antibody titers against swine influenza subtypes determined by the hemagglutination inhibition test are highly dependent on the strain. Abstract from 20th International Pig Veterinary Society Congress, Durban, South Africa.