Analysis of Cell-Derived Microparticles with Highly Precise Nanotechnological Methods

Solène Cherré, Ole Østergaard, Niels H.H. Heegaard, Noemi Rozlosnik

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    Abstract

    Cell-derived microparticles have gained a broad interest in the past years. Being released by blood cells upon activation or induction of apoptosis, they have a great potential as novel diagnostic markers and their investigation can bring new knowledge into the pathogenesis of various diseases. However, new analysis
    methods are required to correctly and reliably investigate these small biological particles (between 50 and 1000 nm). In this work, we aimed at developing an in vitro population of cell-derived microparticles from endothelial cells. The size of the microparticles was analysed by atomic force microscopy.
    Original languageEnglish
    JournalJournal of Nanomaterials & Molecular Nanotechnology
    Issue numberS2
    Number of pages3
    ISSN2324-8777
    DOIs
    Publication statusPublished - 2014
    Event5th International Congress BioNanoMed 2014 - Krems, Austria
    Duration: 26 Mar 201428 Mar 2014
    Conference number: 5

    Conference

    Conference5th International Congress BioNanoMed 2014
    Number5
    CountryAustria
    CityKrems
    Period26/03/201428/03/2014

    Keywords

    • Cell-derived microparticles
    • Atomic force microscopy
    • Apoptosis

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