TY - JOUR
T1 - Analysis of associations between major histocompatibility complex (BoLA) class I haplotypes and subclinical mastitis of dairy cows
AU - Aarestrup, Frank Møller
AU - Jensen, N. E.
AU - Østergård, H.
PY - 1995
Y1 - 1995
N2 - The associations between BoLA class I haplotypes and subclinical mastitis were investigated using information on 333 cows from three different breeds and crossbreeds from 14 dairy herds in Denmark. Somatic cell count and bacteriological status were used as markers for subclinical mastitis. Associations between BoLA class I haplotypes and IMI status were also determined. The association between BoLA class I haplotypes and subclinical mastitis was weak. The A10(W50), A11, A12(A30), A16, A19(A6), A21, A26, and A31(A30) alleles were associated with different markers of subclinical mastitis. Susceptibility or resistance to the two bacteria categories was associated with different alleles. This study indicated that BoLA antigens may be involved in resistance to mastitis and that resistance may be specific for a particular pathogen.
AB - The associations between BoLA class I haplotypes and subclinical mastitis were investigated using information on 333 cows from three different breeds and crossbreeds from 14 dairy herds in Denmark. Somatic cell count and bacteriological status were used as markers for subclinical mastitis. Associations between BoLA class I haplotypes and IMI status were also determined. The association between BoLA class I haplotypes and subclinical mastitis was weak. The A10(W50), A11, A12(A30), A16, A19(A6), A21, A26, and A31(A30) alleles were associated with different markers of subclinical mastitis. Susceptibility or resistance to the two bacteria categories was associated with different alleles. This study indicated that BoLA antigens may be involved in resistance to mastitis and that resistance may be specific for a particular pathogen.
KW - MASTITIS
KW - BOLA
KW - MAJOR HISTOCOMPATIBILITY
KW - STAPHYLOCOCCI
U2 - 10.3168/jds.S0022-0302(95)76793-5
DO - 10.3168/jds.S0022-0302(95)76793-5
M3 - Journal article
SN - 0022-0302
VL - 78
SP - 1684
EP - 1692
JO - Journal of Dairy Science
JF - Journal of Dairy Science
IS - 8
ER -